DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mfrn and NARS2

DIOPT Version :9

Sequence 1:	NP_651600.1	Gene:	mfrn / 43353	FlyBaseID:	FBgn0039561	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_078954.4	Gene:	NARS2 / 79731	HGNCID:	26274	Length:	477	Species:	Homo sapiens

Alignment Length:	109	Identity:	23/109 - (21%)
Similarity:	45/109 - (41%)	Gaps:	17/109 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LSPPTKNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLN 109
            |..|.:|...|....| ::.:..|..:.||...|...||.   :.|....::...|:|
Human   203 LKVPEENFFNVPAFLT-VSGQLHLEVMSGAFTQVFTFGPT---FRAENSQSRRHLAEF------- 256

  Fly   110 YVISGAVATLIHDAISSPTDVIKQRMQMYNSPYTSVVS-CVRDI 152
            |:|...::.:  |::.....||:   :::.:....|:| |..|:
Human   257 YMIEAEISFV--DSLQDLMQVIE---ELFKATTMMVLSKCPEDV 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	Mito_carr	13..98	CDD:278578	12/52 (23%)
		PTZ00168	17..280	CDD:185494	23/109 (21%)
		Mito_carr	107..190	CDD:278578	9/47 (19%)
		Mito_carr	<215..282	CDD:278578
NARS2	NP_078954.4	asnC	27..474	CDD:235176	23/109 (21%)
		EcAsnRS_like_N	44..120	CDD:239813
		AsxRS_core	133..473	CDD:238399	23/109 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1056670at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010