Protein Alignment mfrn and Slc25a18

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001074517.1
• Gene: Slc25a18 / 71803
• MGIID: 1919053
• Length: 320
• Species: Mus musculus
• Alignment Length: 297
• Identity: 74/297 - (24%)
• Similarity: 128/297 - (43%)
• Gaps: 35/297 - (11%)

  Fly    13 SVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLRPIRGASAV 77
            |:...:..|.|||::....::|:|..|||:|:.........:...|......||.|...|||:..
Mouse    12 SISAKLINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRGAAVN 76

  Fly    78 VLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNY-VISGAVATLIHDAISSPTDVIKQRMQ----- 136
            :....|..::..||.:..::|..:..:.|||.. :::|..|.:....|:.|.:::|.::|
Mouse    77 LTLVTPEKAIKLAANDFLRQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQLQDAGRL 141

  Fly   137 -----------MYNSPYT----------SVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHF 180
                       ..:.||:          |.....|::.:.:|....||..|..|:.::|:..|:|
Mouse   142 AVCHQASASATPTSRPYSTGSTSTHRRPSATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIYF 206

  Fly   181 TTYEFFQNKM---NLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLTR----GMI 238
            ..:... |::   .|..|.:......||..||:.||...|||||:||.:.|.:.||..    |:.
Mouse   207 PLFANL-NQLGVSELTGKASFTHSFVAGCTAGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVT 270

  Fly   239 EASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTY 275
            :.:||::...||..|.:|...|.|...|...|....|
Mouse   271 DCARKLWTQEGPAAFMKGAGCRALVIAPLFGIAQGVY 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	73/293 (25%)
Slc25a18	NP_001074517.1	Mito_carr	9..102	CDD:395101	22/89 (25%)
		Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	11..97		21/84 (25%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	105..215		22/110 (20%)
		Mito_carr	111..209	CDD:395101	18/97 (19%)
		Mito_carr	222..307	CDD:395101	28/84 (33%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	224..313		28/84 (33%)