Protein Alignment mfrn and SLC25A40

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_061331.2
• Gene: SLC25A40 / 55972
• HGNCID: 29680
• Length: 338
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 82/319 - (25%)
• Similarity: 130/319 - (40%)
• Gaps: 65/319 - (20%)

  Fly    18 MTAGAIAGVLEHVVMYPLDSVKTRMQSLSPP-----------------------------TKNMN 53
            |.|.....:|..|::.|||.||.|:|:.:.|                             .|..|
Human    19 MLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGN 83

  Fly    54 IVSTLRT---MITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNY----V 111
            ...||..   :|..||:.....|....::.|.||..:||..|:   :|:|...|....|.    :
Human    84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYD---QLSALLRSKLGENETCIPI 145

  Fly   112 ISGAVATLIHDAISSPTDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQ 176
            ::|.||......:.||.::|:.:||.....|..:...|......:|:.:.:|.:...::.::|:.
Human   146 VAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFS 210

  Fly   177 TIHFTTYEFFQNKMNLERK--YNPP--VHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLTRGM 237
            .:::..||..: |...|:.  |.|.  ::..:||.:|:.||..|.|.||:||...||.      .
Human   211 AMYWYNYEILK-KWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQL------W 268

  Fly   238 IEASRKI---YHMA------------GPLGFFRGTTARVLYSMPATAICWSTYEFFKFY 281
            ...|.||   .||:            |..|.|.|...|::...||.||..|||||.|.:
Human   269 TYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAF 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	81/316 (26%)
SLC25A40	NP_061331.2	Mito_carr	12..136	CDD:395101	29/119 (24%)
		Solcar 1	13..131		27/114 (24%)
		Solcar 2	139..223		16/84 (19%)
		Mito_carr	145..228	CDD:395101	17/83 (20%)
		Mito_carr	231..330	CDD:395101	35/103 (34%)
		Solcar 3	233..327		34/99 (34%)