Protein Alignment mfrn and SLC25A38

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_060345.2
• Gene: SLC25A38 / 54977
• HGNCID: 26054
• Length: 304
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 55/246 - (22%)
• Similarity: 82/246 - (33%)
• Gaps: 76/246 - (30%)

  Fly     1 MENILEP------SSSDDNMPSDNKKDLQSLLSSEDDFFDPPPSSSRRDSSGNEDKPDLRTDFED 59
            :.||||.      |..|..:....|.|...||||..:.|.            |::......|..|
Human   386 INNILEDRLAPELSQLDRGLERQVKPDPTPLLSSRHNIFQ------------NDEFDVFSRDSVD 438

  Fly    60 IIMPEMG---HDNSILMVKDQKDRERDKRKETKSKRELEEEEREKMQVLVSNFTEEQLDRY---- 117
            :.....|   .:|...:|.|::......::..|....:||...:..:....::.:|..|.|
Human   439 LSRVHKGRRKEENVRSLVNDKQAVVAQWQRYQKYSVVVEEVPLQPGEYQADDYEDEYDDTYDGNQ 503

  Fly   118 ----------EMYRRAAFPKAAVKRLMQTITGCSVSQNVVIAMSGIAKVFVGEVVEEALDVMEKA 172
                      |:..|..|   .:.::::|                   ...|||.||..|..::.
Human   504 VGANDADSDDELISRRPF---TIPQVLRT-------------------KMPGEVQEEEWDEEDEV 546

  Fly   173 GETGA-----IQ-PKYLRE--AVRR---LRNKGHIP------TG--RGHKQ 204
            .|...     || |..|||  ..||   |..||:.|      ||  |||.|
Human   547 EEEAPKPDHFIQDPAVLREKAEARRMAFLARKGYRPENSTAVTGGPRGHGQ 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	49/224 (22%)
SLC25A38	NP_060345.2	Solcar 1. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	25..114
		Mito_carr	26..117	CDD:395101
		Mito_carr	120..209	CDD:395101
		Solcar 2. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	121..205
		Solcar 3. /evidence=ECO:0000255|HAMAP-Rule:MF_03064	215..299
		Mito_carr	217..304	CDD:395101