Protein Alignment mfrn and SLC25A39

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: XP_011523182.1
• Gene: SLC25A39 / 51629
• HGNCID: 24279
• Length: 365
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 83/361 - (22%)
• Similarity: 148/361 - (40%)
• Gaps: 103/361 - (28%)

  Fly    18 MTAGAIAGVLEHVVMYPLDSVKTRMQSLSP-------PTKNM----------NIVSTLRTMITRE 65
            |.|.....|:..:.|.|||.||.|:||..|       |:..:          ::.||.:.::...
Human    15 MVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGKCLLYCN 79

  Fly    66 GLLRPI---------------------------------------RGASAVVLGAGPAHSLYFAA 91
            |:|.|:                                       .|..|.::...||.::||.|
Human    80 GVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTA 144

  Fly    92 YE----------MTKELTAKFTSVRNLNYVISGAVATLIHDAISSPTDVIKQRMQMYNSPYTSVV 146
            |:          :|.:|.|.         :::||:|.|....:.||.::::.::|..:..|..:.
Human   145 YDQLKAFLCGRALTSDLYAP---------MVAGALARLGTVTVISPLELMRTKLQAQHVSYRELG 200

  Fly   147 SCVRDIYKREGFKAFYRAYGTQLVMNLPY------QTIHFTTYEFFQNKMN-LERKYNPPVHMA- 203
            :|||....:.|:::.:..:|...:.::|:      |.:::..||..::.:| ...|....|.|:
Human   201 ACVRTAVAQGGWRSLWLGWGPTALRDVPFSVHPPPQALYWFNYELVKSWLNGFRPKDQTSVGMSF 265

  Fly   204 -AGAAAGACAAAVTTPLDVIKTLLNTQETGLTRGMIEA--------------SRKIYHMAGPLGF 253
             ||..:|..||.:|.|.||:||     :..:..|.:||              .|:|...:|..|.
Human   266 VAGGISGTVAAVLTLPFDVVKT-----QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGL 325

  Fly   254 FRGTTARVLYSMPATAICWSTYEFFKFYLCGLDADQ 289
            |.|...|::.:.|:.||..|||||.|.:...|:.|:
Human   326 FAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	80/350 (23%)
SLC25A39	XP_011523182.1	Mito_carr	9..152	CDD:395101	27/136 (20%)
		Mito_carr	161..252	CDD:395101	19/99 (19%)
		Mito_carr	257..356	CDD:395101	32/103 (31%)