Protein Alignment mfrn and SLC25A37

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_057696.2
• Gene: SLC25A37 / 51312
• HGNCID: 29786
• Length: 338
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 157/303 - (51%)
• Similarity: 207/303 - (68%)
• Gaps: 33/303 - (10%)

  Fly     4 DDYESLPTT-SVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNM--NIVSTLRTMITRE 65
            :|||:|||: ||..:|||||:||:|||.||||:||||||||||||..|..  :|...|:.::..|
Human    34 EDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTE 98

  Fly    66 GLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYV------------ISGAVAT 118
            |..||:||.:.:::||||||::|||.||..|         |.||.|            |:|::||
Human    99 GFWRPLRGVNVMIMGAGPAHAMYFACYENMK---------RTLNDVFHHQGNSHLANGIAGSMAT 154

  Fly   119 LIHDAISSPTDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTY 183
            |:|||:.:|.:|:|||:|||||.:.|.:||:|.:::.||..||||:|.|||.||:|:|:|||.||
Human   155 LLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITY 219

  Fly   184 EFFQNKMNLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQE---------TGLTRGMIE 239
            ||.|.::|..|.|||..|:.:|..|||.|||.||||||.||||||||         :|...||..
Human   220 EFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMAN 284

  Fly   240 ASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYL 282
            |.|.:|.:.|..|:|:|..|||:|.||:|||.||.|||||::|
Human   285 AFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	147/285 (52%)
SLC25A37	NP_057696.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		5/7 (71%)
		Solcar 1	43..131		49/96 (51%)
		Mito_carr	44..136	CDD:395101	52/100 (52%)
		Solcar 2	141..225		44/83 (53%)
		Mito_carr	142..224	CDD:395101	43/81 (53%)
		Solcar 3	232..326		51/93 (55%)
		Mito_carr	<252..330	CDD:395101	41/76 (54%)