Protein Alignment mfrn and SLC25A41

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_775908.2
• Gene: SLC25A41 / 284427
• HGNCID: 28533
• Length: 370
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 76/293 - (25%)
• Similarity: 134/293 - (45%)
• Gaps: 25/293 - (8%)

  Fly     1 MNIDDYESLPTTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITRE 65
            :.:|:.|:|     ...:.:||:||.:......|||..|..||..|..|...|::..|::|:...
Human    84 LEVDNKEAL-----WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEG 143

  Fly    66 GLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRN----LNYVISGAVATLIHDAISS 126
            |.....||....||...|.:::.|:.:|..|..   |..::.    ...:::|::|..|...:.:
Human   144 GFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNY---FCGIQGSPPFQERLLAGSLAVAISQTLIN 205

  Fly   127 PTDVIKQRMQMYNS-PYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQ-NK 189
            |.:|:|.|:.:..: .|..::.|.|.|.:|||.:|.||.|...::..:||.......||..| ..
Human   206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFW 270

  Fly   190 MNLERKYNPP---VHMAAGAAAGACAAAVTTPLDVIKTLLNTQET-----GLTRGMIEASRKIYH 246
            :...|....|   |.:::...:..|....:.||.:::|.:..|:|     ...||:::   :|..
Human   271 VKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQ---RILA 332

  Fly   247 MAGPLGFFRGTTARVLYSMPATAICWSTYEFFK 279
            ..|.||.:||.|..:|..:||..|.:..||..|
Human   333 QQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMK 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	73/277 (26%)
SLC25A41	NP_775908.2	PTZ00169	87..368	CDD:240302	76/290 (26%)
		Solcar 1. /evidence=ECO:0000255	90..176		26/90 (29%)
		Solcar 2. /evidence=ECO:0000255	184..269		23/84 (27%)
		Solcar 3. /evidence=ECO:0000255	280..367		24/89 (27%)