Protein Alignment mfrn and mfn-1

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001382726.1
• Gene: mfn-1 / 174752
• WormBaseID: WBGene00012204
• Length: 318
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 157/304 - (51%)
• Similarity: 196/304 - (64%)
• Gaps: 25/304 - (8%)

  Fly     4 DDYESLPTTSV--GVNMTAGAIAGVLEHVVMYPLDSVKTRMQSL--SPPTKNMNIVSTLRTMITR 64
            |:||||||.||  .|::||||:||.:||.||:|.||||||||||  .|.||....|.:|.:::.|
 Worm     7 DEYESLPTHSVPIQVHLTAGALAGAVEHCVMFPFDSVKTRMQSLCPCPETKCPTPVHSLMSIVKR 71

  Fly    65 EGLLRPIRGASAVVLGAGPAHSLYFAAYEMTK-ELTAKFTSVRN-LNYVISGAVATLIHDAISSP 127
            ||.|||:||.:||..|:.|||:|||..||..| .||.......| |.|..||.|||||||||.:|
 Worm    72 EGWLRPLRGVNAVAAGSMPAHALYFTVYEKMKGYLTGNSAGHSNTLAYGASGVVATLIHDAIMNP 136

  Fly   128 TDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNL 192
            .:|:||||||..|||.|.:.|.|.:|.|||..||||:|.|||.||:|:|.|||.:|||:|:.:|.
 Worm   137 AEVVKQRMQMAFSPYGSSLECARCVYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYEFWQHVLNP 201

  Fly   193 ERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLT-------------------RGMI 238
            |.||:|..|:.||..||..|||:|||:|.:||:||||:....                   ||:.
 Worm   202 EHKYDPKSHLIAGGLAGGLAAALTTPMDCVKTVLNTQQAAEADPANRRIFLQNELQARYRYRGIS 266

  Fly   239 EASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYL 282
            :|.|.||...|..||..|..|||::.:||||:.||.||.|||.|
 Worm   267 DAVRTIYSQRGLSGFSCGLQARVIFQVPATALSWSVYELFKFML 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	144/285 (51%)
mfn-1	NP_001382726.1	Mito_carr	16..110	CDD:395101	51/93 (55%)
		Mito_carr	112..199	CDD:395101	51/86 (59%)
		Mito_carr	<225..314	CDD:395101	35/86 (41%)