Protein Alignment mfrn and SLC25A25

DIOPT Version :10

• Sequence 1: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001317917.1
• Gene: SLC25A25 / 114789
• HGNCID: 20663
• Length: 515
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 91/336 - (27%)
• Similarity: 137/336 - (40%)
• Gaps: 57/336 - (16%)

  Fly     1 MNID-----DY------ESLPTT----------SVGVNMT--------------------AGAIA 24
            |.||     ||      |::|..          .||.|:|                    ||..|
Human   178 MTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGA 242

  Fly    25 GVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLRPI-RGASAVVLGAGPAHSLY 88
            |.:......|||.:|..||..:..:.||.||.....|| |||..|.: ||....||...|..::.
Human   243 GAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMI-REGGARSLWRGNGINVLKIAPESAIK 306

  Fly    89 FAAYEMTKELT-AKFTSVRNLNYVISGAVATLIHDAISSPTDVIKQRMQMYNS-PYTSVVSCVRD 151
            |.|||..|.|. :...::|....:::|::|..|..:...|.:|:|.||.:..: .|:.::.|.|.
Human   307 FMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARR 371

  Fly   152 IYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNLERKYNPP-----VHMAAGAAAGAC 211
            |..|||..|||:.|...::..:||..|....||..:|........|..     |.:|.|..:..|
Human   372 ILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTC 436

  Fly   212 AAAVTTPLDVIKTLLNTQETGLTRGMIEAS-----RKIYHMAGPLGFFRGTTARVLYSMPATAIC 271
            ....:.||.:::|.:..|.:  ..|..|.:     :.|....|..|.:||.....:..:||.:|.
Human   437 GQLASYPLALVRTRMQAQAS--IEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 499

  Fly   272 WSTYEFFKFYL 282
            :..||..|..|
Human   500 YVVYENLKITL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	80/295 (27%)
SLC25A25	NP_001317917.1	FRQ1	49..189	CDD:444056	4/10 (40%)
		PTZ00169	237..491	CDD:240302	73/256 (29%)