DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mfrn and slc25a37

DIOPT Version :9

Sequence 1:	NP_651600.1	Gene:	mfrn / 43353	FlyBaseID:	FBgn0039561	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	XP_002932597.1	Gene:	slc25a37 / 100379786	XenbaseID:	XB-GENE-999414	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	154/294 - (52%)
Similarity:	202/294 - (68%)	Gaps:	15/294 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DDYESLPT-TSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNM--NIVSTLRTMITRE 65
            |:|||||. .|...:|.|||:||:|||.||||:||||||||||.|..|..  .:...|:.:|..|
Frog    24 DEYESLPPGASPLTHMMAGAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQYRGVTEALKRIIRTE 88

  Fly    66 GLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYV---ISGAVATLIHDAISSP 127
            ||..|:||.:..:|||||||:||||.||..|.......:....::|   ::|::|||:|||:.:|
Frog    89 GLFTPLRGINVTMLGAGPAHALYFACYEKMKTTVGGMINHAGNSHVANGVAGSLATLLHDAVMNP 153

  Fly   128 TDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNL 192
            .:|:|||||||||||.|::.|::.:.:.||..||||:|.|||.||:|:|.|||.||||.|.::|.
Frog   154 AEVVKQRMQMYNSPYRSMLHCIQSVSRTEGIGAFYRSYSTQLFMNIPFQAIHFITYEFTQEQLNP 218

  Fly   193 ERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQE---------TGLTRGMIEASRKIYHMA 248
            :|:|:|..|:.:||.|||.|||.||||||.||||||||         :|...||:...|.:|.:.
Frog   219 QRQYHPGSHIVSGAIAGAVAAAATTPLDVCKTLLNTQENTVLSSVNISGHLSGMVNTFRTVYQLG 283

  Fly   249 GPLGFFRGTTARVLYSMPATAICWSTYEFFKFYL 282
            |..|||||..|||:|.||:|||.||.|||||::|
Frog   284 GVAGFFRGVQARVIYQMPSTAIAWSVYEFFKYFL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mfrn	NP_651600.1	Mito_carr	13..98	CDD:278578	48/86 (56%)
		PTZ00168	17..280	CDD:185494	145/276 (53%)
		Mito_carr	107..190	CDD:278578	45/85 (53%)
		Mito_carr	<215..282	CDD:278578	41/75 (55%)
slc25a37	XP_002932597.1	Mito_carr	34..124	CDD:365909	48/89 (54%)
		Mito_carr	132..216	CDD:365909	45/83 (54%)
		Mito_carr	<242..319	CDD:365909	42/76 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6174
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74739
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2567
OMA	1	1.010	-	-		QHG53563
OrthoDB	1	1.010	-	-		D1056670at2759
OrthoFinder	1	1.000	-	-		FOG0001524
OrthoInspector	1	1.000	-	-		otm48712
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1812
SonicParanoid	1	1.000	-	-		X1097
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010