DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NSD and ASHH1

DIOPT Version :9

Sequence 1:	NP_733239.1	Gene:	NSD / 43351	FlyBaseID:	FBgn0039559	Length:	1427	Species:	Drosophila melanogaster
Sequence 2:	NP_001321484.1	Gene:	ASHH1 / 844005	AraportID:	AT1G76710	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	228	Identity:	86/228 - (37%)
Similarity:	123/228 - (53%)	Gaps:	8/228 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly  1153 QSGNKLHPPPYVKIKTNKAVPPLRFSQNLEDLSTCNC---LPVDEHPCGPEAGCLNRMLFNECNP 1214
            |.|::|  |.|..|..|.........|..||:|.|.|   ....:..||..  |||.:...||.|
plant     9 QEGDEL--PQYEHIYQNDFSYRKHKKQKEEDISICECKFDFGDPDSACGER--CLNVITNTECTP 69

  Fly  1215 EYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQ 1279
            .||..|..|:|:.|::.:..:.:::....||:|||..|.|..|.|::||.||||:..|.::|.:.
plant    70 GYCPCGVYCKNQKFQKCEYAKTKLIKCEGRGWGLVALEEIKAGQFIMEYCGEVISWKEAKKRAQT 134

  Fly  1280 KQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNS 1344
            .:....::.|.:.:.....|||..||:||||:||||.|||||:||.|....||||||.:.|...:
plant   135 YETHGVKDAYIISLNASEAIDATKKGSLARFINHSCRPNCETRKWNVLGEVRVGIFAKESISPRT 199

  Fly  1345 ELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGK 1377
            ||.::|.: :....:|..|.|||..|||.:|.|
plant   200 ELAYDYNF-EWYGGAKVRCLCGAVACSGFLGAK 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NSD	NP_733239.1	MSH6_like	391..508	CDD:99898
		PHD2_NSD	867..932	CDD:277040
		PHD3_NSD	933..988	CDD:277041
		PHD4_NSD	1001..1041	CDD:277042
		WHSC1_related	1047..1141	CDD:99899
		AWS	1183..1233	CDD:197795	18/52 (35%)
		SET	1234..1354	CDD:214614	49/119 (41%)
ASHH1	NP_001321484.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001511
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22884
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010