Protein Alignment NSD and SUVR2

DIOPT Version :10

• Sequence 1: NP_733239.1
• Gene: NSD / 43351
• FlyBaseID: FBgn0039559
• Length: 1427
• Species: Drosophila melanogaster
• Sequence 2: NP_974880.1
• Gene: SUVR2 / 834422
• AraportID: AT5G43990
• Length: 740
• Species: Arabidopsis thaliana
• Alignment Length: 998
• Identity: 182/998 - (18%)
• Similarity: 307/998 - (30%)
• Gaps: 401/998 - (40%)

  Fly   469 KAFDDMR----EELRIKHGPKS--AKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQT 527
            |||..||    |:.|:|...|:  |.|.:.         |....|:       .|....:..:.:
plant    32 KAFMAMRAMGIEDARVKPVLKNLLALYEKN---------WELIAED-------NYRVLADAIFDS 80

  Fly   528 YENVVTLNRQKRKRTKYMMQD---TSDVGSSLYDSTDNLHNKQGTQLLAVKRERSESPFSPAFSP 589
            :|: ..:...:.|:...:.:|   .::|             .:|.:.|....|..|...:.:..|
plant    81 HED-QAIQESEEKKADEVKEDEGCAAEV-------------DRGKKKLHESIEDDEDVMAESDRP 131

  Fly   590 VKSKNEKRAKRRKLSNGTEADTGSNSMAVTPSQTETTVDSSAYENPEFRQLLSAVMEYVMMNRSD 654
            :     ||.:||        ..|.:::| :||....|::..:..:.|...:|.......:.|..|
plant   132 L-----KRLRRR--------GEGGSALA-SPSLGSPTLEGPSINDEENAPILLPYHPVPIENDHD 182

  Fly   655 ------EKVEKVLLSVVSNI-WSLKQIQLRELERDLASGEIEEPLGSSVV---GRGSGVG--TIK 707
                  .|||.:....:|:| .|:.:.....||.|.::|.:||..|.:|.   |..:.:.  |:.
plant   183 AGELILTKVEPITNMPLSSIPDSVDRGDSSMLEIDKSNGHVEEKAGETVSTADGTTNDISPTTVA 247

  Fly   708 RLSNRLMTMMVRRSMTPVVTPSTTPAPSEPDRRLSEPPKT---------KKPVNRPIEE-VIEDI 762
            |.|:..:...:..   |......:.|..|....||..|.|         .:.:.|.:|| .:...
plant   248 RFSDHKLAATIEE---PPALELASSASGEVKINLSFAPATGGSNPHLPSMEELRRAMEEKCLRSY 309

  Fly   763 LQLDSKYLFRGLSREPICKYCY---------------------------------------QAGS 788
            ..||..:...|...: ||. ||                                       ||.:
plant   310 KILDPNFSVLGFMND-ICS-CYLDLATNGRDSANQLPKNLPFVTTNIDALKKSAARMAYTSQASN 372

  Fly   789 DLVRCSRTCSSWLHADCLERKVTGAPMPKIGSRKALVIPPTSKSPSPDEDHVTADAKEVV-AVGT 852
            |:|..           |....:..|....:|...|||:.|        |..::||...:: :||
plant   373 DVVEI-----------CSNEHMRDAENGAVGDSMALVVVP--------ECQLSADEWRLISSVG- 417

  Fly   853 SLVCHECNVGEPEGCVICHQVESPAVPSTPRKEDSSSHTPIEDKLLTCSQPMCGKRFHTSCCKYW 917
                 :.::|:       ..||.|.|            ..:.||:    .|:    ||
plant   418 -----DISLGK-------ETVEIPWV------------NEVNDKV----PPV----FH------- 443

  Fly   918 PQASSSKHSARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTN 982
                          ::..:.|..|.:.|| .||:.:..:|  |.:
plant   444 --------------YIAQSLVYQDAAVKF-SLGNIRDDQC--CSS-------------------- 471

  Fly   983 IICPRHNIAKADAHVNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLP 1047
                                          ||..| :|....||              |.:.
plant   472 ------------------------------CCGDC-LAPSMACR--------------CATA--- 488

  Fly  1048 LYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFG-THDHGWISRRRVYLYIEG 1111
                     ||.|.:....:|               :.||:.:... ..|    .|:::.||
plant   489 ---------FNGFAYTVDGLL---------------QEDFLEQCISEARD----PRKQMLLY--- 522

  Fly  1112 DTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLR 1176
                                   .:..|:.||:::
plant   523 -----------------------CKECPLEKAKKE------------------------------ 534

  Fly  1177 FSQNLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEYCKAGSL--CENRMFEQRKSPRLEVV 1239
                           |...||   .|.|.|....||   :.|.|.:  |.||:.:|....:|:|.
plant   535 ---------------VILEPC---KGHLKRKAIKEC---WSKCGCMKNCGNRVVQQGIHNKLQVF 578

  Fly  1240 YM-NERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFL----------GV 1293
            :. |.||:||...|.:..|.||.|..||::...|..:|:.    ||..:...|          |.
plant   579 FTPNGRGWGLRTLEKLPKGAFVCELAGEILTIPELFQRIS----DRPTSPVILDAYWGSEDISGD 639

  Fly  1294 EKDFIIDAGPKGNLARFMNHSC--------EPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNY 1350
            :|...::....||::||:||.|        ..:.||   |.:..:.:..|..::|....|||::|
plant   640 DKALSLEGTHYGNISRFINHRCLDANLIEIPVHAET---TDSHYYHLAFFTTREIDAMEELTWDY 701

  Fly  1351 ---LWDDLMNNSKKACFCGAKRC 1370
               ...|:...|...|.||:..|
plant   702 GVPFNQDVFPTSPFHCQCGSDFC 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSD	NP_733239.1	PWWP_NSD_rpt1	395..514	CDD:438972	13/50 (26%)
		PHD2_NSD	867..932	CDD:277040	9/64 (14%)
		PHD3_NSD	933..988	CDD:277041	8/54 (15%)
		PHD4_NSD	1001..1041	CDD:277042	6/39 (15%)
		PWWP_NSD_rpt2	1048..1143	CDD:438963	11/95 (12%)
		AWS	1183..1233	CDD:197795	14/51 (27%)
		SET_NSD	1233..1375	CDD:380950	43/160 (27%)
SUVR2	NP_974880.1	WIYLD	29..83	CDD:431288	14/66 (21%)
		SET_SETDB-like	440..702	CDD:380936	81/469 (17%)