DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NSD and ASHH4

DIOPT Version :9

Sequence 1:	NP_733239.1	Gene:	NSD / 43351	FlyBaseID:	FBgn0039559	Length:	1427	Species:	Drosophila melanogaster
Sequence 2:	NP_001319802.1	Gene:	ASHH4 / 825166	AraportID:	AT3G59960	Length:	329	Species:	Arabidopsis thaliana

Alignment Length:	282	Identity:	87/282 - (30%)
Similarity:	146/282 - (51%)	Gaps:	30/282 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1142 KARRQEQDMER-QSGNKLHPPPYVKIKTNKAVPPLRFSQNLED---LSTCNCLPVDEHPCGPEAG 1202
            |.::|..::|: :|.::|:....:.||.|..:.. :..:.::|   ..:|:..|.....||.:..
plant    19 KLKKQIGELEKLESPDRLNNVKPIFIKRNIYLKK-KLKKKVKDHGIFCSCSLDPGSSTLCGSDCN 82

  Fly  1203 CLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEV 1267
            |  .:|.:.|:.. ||..|.|.|:.|:||...::::|...:.|:|:|..|.|..|:|:|||||||
plant    83 C--GILLSSCSSS-CKCSSECTNKPFQQRHIKKMKLVQTEKCGYGIVADEDINSGEFIIEYVGEV 144

  Fly  1268 INHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRV 1332
            |:....:.|:.:.....:.|:|...:..:.:|||..|||.:|::||||.||.|.|||.::...|:
plant   145 IDDKICEERLWKLNHKVETNFYLCQINWNMVIDATHKGNKSRYINHSCSPNTEMQKWIIDGETRI 209

  Fly  1333 GIFAIKDIPVNSELTFNYLWDDLMNNSKKACFCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKA 1397
            ||||.:.|....:||::|.:  :...:.:.|:|||..|..::|.|        ..|.|.....:|
plant   210 GIFATRFINKGEQLTYDYQF--VQFGADQDCYCGAVCCRKKLGAK--------PCKTKNTTLEEA 264

  Fly  1398 SAVRIHVKPK------KTPKVK 1413
                  |||.      ||||.|
plant   265 ------VKPVACKVTWKTPKGK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NSD	NP_733239.1	MSH6_like	391..508	CDD:99898
		PHD2_NSD	867..932	CDD:277040
		PHD3_NSD	933..988	CDD:277041
		PHD4_NSD	1001..1041	CDD:277042
		WHSC1_related	1047..1141	CDD:99899
		AWS	1183..1233	CDD:197795	16/52 (31%)
		SET	1234..1354	CDD:214614	45/119 (38%)
ASHH4	NP_001319802.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1081
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22884
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910