Protein Alignment NSD and set3

DIOPT Version :9

• Sequence 1: NP_733239.1
• Gene: NSD / 43351
• FlyBaseID: FBgn0039559
• Length: 1427
• Species: Drosophila melanogaster
• Sequence 2: NP_594837.1
• Gene: set3 / 2541899
• PomBaseID: SPAC22E12.11c
• Length: 859
• Species: Schizosaccharomyces pombe
• Alignment Length: 503
• Identity: 104/503 - (20%)
• Similarity: 165/503 - (32%)
• Gaps: 174/503 - (34%)

  Fly  1000 LWCYICV-----KGGELVCCETCPIAVHAHCRNIPI-KTNESYICEECESGRLPLYGE----IVW 1054
            :|...||     ..|..:.||:|.:..||.|.||.. ...|.|.||:|:.  .|:..:    |..
pombe     1 MWKIRCVCPFEDDDGFTIQCESCEVWQHAVCVNIDANNVPEKYFCEQCQP--RPIDADKAHKIQL 63

  Fly  1055 AKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFG------THDHGWISRRRVYLYIEGDT 1113
            |:           |...|..|.||.::...|:.....||      ||.   .|.|:     ..:|
pombe    64 AR-----------LQREEEQSRILSRSRSSNNKRRTSFGKNGASPTHS---ASPRQ-----GNNT 109

  Fly  1114 G--------DGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPP-------- 1162
            |        ..:.:.|..:||..||..     ||  .|........|:..|.|:.||
pombe   110 GANGALFSQSTNSSNSGSYRNSVTGAT-----LP--NAHAPHSQNRRRRSNHLNNPPEAPITEAS 167

  Fly  1163 ----------YVKIKTNK-AVPPLRFSQNLEDLSTCNCLPVDEHPCGPEAGCLNRMLFNECNPEY 1216
                      ||.:::|. :...|.:|:|| ||..     :||          :.:|.:.|....
pombe   168 NEYVYSFHLEYVPLESNTFSASALEYSKNL-DLKN-----LDE----------SEVLMDGCQVVP 216

  Fly  1217 CKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQ 1281
            ..:...|.:|                   ||||:...|.....::|..|.|....|:       :
pombe   217 ISSSKFCCSR-------------------FGLVSTCEIPPNTPIMEVKGRVCTQNEY-------K 255

  Fly  1282 RDRDENYYFLGVEK---------DFIIDAGPKGNLARFMNHSCEPNC------------------ 1319
            .|....|..||..|         ..::|:...|:.|||....|:.|.
pombe   256 SDPKNQYNILGAPKPHVFFDSNSQLVVDSRVAGSKARFARKGCQSNSVVSSVYMNGSNSVPRFIL 320

  Fly  1320 --------ETQ---KWTVNCIHRVGIFA---------IKDIPVNSELTFNYL-WDDLMNNSKKAC 1363
                    ||:   .||::..|....||         ::::.:.||:...:| :::..:..||.|
pombe   321 YSTTHIAPETEIIGDWTLDISHPFRQFAPGMSRPSFNMEELELLSEVLSTFLSFNECASQDKKNC 385

  Fly  1364 -FCGAKRCSGEIGGKLKDDAVKAHAKLKQMRRAKASAVRIHVKPKKTP 1410
             |....:            .:||..:.....|...:..|:.:.|..||
pombe   386 VFSRVTK------------YIKAARRASTANRVSVAKDRLSLTPSSTP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSD	NP_733239.1	MSH6_like	391..508	CDD:99898
		PHD2_NSD	867..932	CDD:277040
		PHD3_NSD	933..988	CDD:277041
		PHD4_NSD	1001..1041	CDD:277042	16/45 (36%)
		WHSC1_related	1047..1141	CDD:99899	24/111 (22%)
		AWS	1183..1233	CDD:197795	8/49 (16%)
		SET	1234..1354	CDD:214614	31/167 (19%)
set3	NP_594837.1	PHD_MLL5	5..48	CDD:277025	15/42 (36%)
		SET	215..343	CDD:214614	27/153 (18%)
		SET	284..826	CDD:225491	27/150 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030