DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL4 and Rpl4

DIOPT Version :9

Sequence 1:	NP_524538.2	Gene:	RpL4 / 43349	FlyBaseID:	FBgn0003279	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_071955.1	Gene:	Rpl4 / 64302	RGDID:	619824	Length:	421	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	252/409 - (61%)
Similarity:	306/409 - (74%)	Gaps:	14/409 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESW 70
            ||||:|||:||.| :..||:.||||||||||||:||.||..||:||||.||||||||||||||||
  Rat     4 ARPLISVYSEKGE-SSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESW 67

  Fly    71 GTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASG 135
            ||||||||||||||||||||||||||||||||||||||||:|||||:||..|:|||:.||:|||.
  Rat    68 GTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASA 132

  Fly   136 VPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMR 200
            :||||.||||.::.|.|.||||.|:|:..:|||:||..|::||.|.||:|||.|||.|||:|.||
  Rat   133 LPALVMSKGHCVEEVPELPLVVEDKVESYKKTKEAVQLLKKLKAWNDIKKVYASQRMRAGKGKMR 197

  Fly   201 DRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLND 265
            :||||.||||.::|::|.|:.|||||||||..:||.|||:||||||||||||.|||||||.:|::
  Rat   198 NRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDE 262

  Fly   266 LFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRSVRRLNPLTNVRQLIK 330
            |:|||:|.::||..||||..||.||||||:|||.||::.||.|||::.|.|.:.|||.|:|.::|
  Rat   263 LYGTWRKAASLKSNYNLPMHKMMNTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLK 327

  Fly   331 LNPYAEVLKRRAALAAEKR----------TVAKVLAKAKKQNVELA---KSHFANVATKAAANRA 382
            |||||:.::|...|...:.          ..|.:.||::|...|..   |........|...:..
  Rat   328 LNPYAKTMRRNTILRQARNHKLRVKKLEAAAAALAAKSEKIVPEKGAGDKKPAVGKKGKKPVDAK 392

  Fly   383 KLLAARKKKVAAKKPAAKK 401
            ||.....|||..||||.||
  Rat   393 KLKKPAGKKVVTKKPAEKK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL4	NP_524538.2	PTZ00428	6..383	CDD:185611	241/389 (62%)
		Ribosomal_L4	10..268	CDD:294231	187/257 (73%)
		Ribos_L4_asso_C	278..350	CDD:291072	37/81 (46%)
Rpl4	NP_071955.1	PTZ00428	2..350	CDD:185611	234/346 (68%)
		Ribosomal_L4	10..265	CDD:294231	186/255 (73%)
		Ribos_L4_asso_C	275..348	CDD:291072	37/72 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	365..421		15/47 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341897
Domainoid	1	1.000	375	1.000	Domainoid score	I836
eggNOG	1	0.900	-	-		E1_COG0088
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H748
Inparanoid	1	1.050	498	1.000	Inparanoid score	I1327
OMA	1	1.010	-	-		QHG53550
OrthoDB	1	1.010	-	-		D438133at33208
OrthoFinder	1	1.000	-	-		FOG0003183
OrthoInspector	1	1.000	-	-		oto96596
orthoMCL	1	0.900	-	-		OOG6_100849
Panther	1	1.100	-	-	LDO	PTHR19431
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2143
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770