Protein Alignment RpL4 and RPL4

DIOPT Version :10

• Sequence 1: NP_524538.2
• Gene: RpL4 / 43349
• FlyBaseID: FBgn0003279
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_000959.2
• Gene: RPL4 / 6124
• HGNCID: 10353
• Length: 427
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 258/426 - (60%)
• Similarity: 311/426 - (73%)
• Gaps: 42/426 - (9%)

  Fly     6 ARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESW 70
            ||||:|||:||.| :..||:.||||||||||||:||.||..||:||||.||||||||||||||||
Human     4 ARPLISVYSEKGE-SSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESW 67

  Fly    71 GTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASG 135
            ||||||||||||||||||||||||||||||||||||||||:|||||:||..|:|||:.||:|||.
Human    68 GTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASA 132

  Fly   136 VPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMR 200
            :||||.||||.|:.|.|.||||.|:|:..:|||:||:.|::||.|.||:|||.|||.|||:|.||
Human   133 LPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMR 197

  Fly   201 DRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLND 265
            :||||.||||.::|::|.|:.|||||||||..:||.|||:||||||||||||.|||||||.:|::
Human   198 NRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDE 262

  Fly   266 LFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRSVRRLNPLTNVRQLIK 330
            |:|||:|.::||..||||..||.||||||:|||.||::.||.|||::.|.|.:.|||.|:|.::|
Human   263 LYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLK 327

  Fly   331 LNPYAEVLKR------------------------------RAALAAEKRTVAKVLAKAKKQNVEL 365
            |||||:.::|                              :||:|.:|..|.|   |.||..|.:
Human   328 LNPYAKTMRRNTILRQARNHKLRVDKAAAAAAALQAKSDEKAAVAGKKPVVGK---KGKKAAVGV 389

  Fly   366 AKSHFANVATKAAANRAKLLAARKKKVAAKKPAAKK 401
            .|.....|..||||.        ||....||||.||
Human   390 KKQKKPLVGKKAAAT--------KKPAPEKKPAEKK 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpL4	NP_524538.2	PTZ00428	6..383	CDD:185611	250/406 (62%)
RPL4	NP_000959.2	PTZ00428	2..372	CDD:185611	236/368 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..427		24/60 (40%)