DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12259 and XCT

DIOPT Version :9

Sequence 1:	NP_651595.1	Gene:	CG12259 / 43347	FlyBaseID:	FBgn0039557	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_179711.2	Gene:	XCT / 816650	AraportID:	AT2G21150	Length:	337	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	150/364 - (41%)
Similarity:	225/364 - (61%)	Gaps:	53/364 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YKGAASEAGRAAQLMKKREIQQQEIEFRKKKIEEELKLDKIENKFATHYD-------------AV 55
            |.|.|.:|.|..:|.|:||.:       :|||:|      :::|.|:..|             .:
plant     8 YVGTAQDAVRIRRLQKQREAE-------RKKIQE------LKSKSASGNDQSGLLQFGTSSCEIL 59

  Fly    56 EQQLKSSTIGLVTLDEMKAKQEDIVREREKKLAQKKDEKDREKQRALEAIQAEKNKQKRQIQA-- 118
            :...|..|:||||.:|...|:.:|    ..|..:::.||.::.|:..|.:|.||..:||:|:.
plant    60 DTAFKKETVGLVTREEYVEKRVNI----RNKFEEEEKEKLQKLQQEEEELQLEKRNKKRKIKGSS 120

  Fly   119 -LSFNLDDDEEEEEEDDEDHDKKQLKIKQEDQPKPKWTEIKEDILPIKKKKICKNPDVDTSFLPD 182
             |||..|.:...:|:|.|:              |...|.      .::..|:.|:|.|:|:||||
plant   121 RLSFAEDFENGSDEDDGEN--------------KSSGTG------NLRCGKLGKDPSVETNFLPD 165

  Fly   183 REREEQENRLREQLRQEWVMQQAELKDEDISITFSYWDGSGHRRNVLMKKGNSIYQFLQKCLELL 247
            .|||.:|...||:|:::|:.:|.::|:|.:.||:|||||:||||.:.::||:.|..||:...:.|
plant   166 SEREAEEQAERERLKKQWLREQEQIKNEPLEITYSYWDGTGHRRVIQVRKGDPIGNFLRAVQQQL 230

  Fly   248 RKEFIELKTVMADQLMYVKEDLILPHHYSFYDFIVTKARGKSGPLFQFDVHDDVRMISDASVEKE 312
            ..:|.|::|...:.|:|||||||:||.:|||:.|:.||||||||||.||||:|||.|:||::||:
plant   231 APDFREIRTASVENLLYVKEDLIIPHQHSFYELIINKARGKSGPLFHFDVHEDVRTIADATIEKD 295

  Fly   313 ESHAGKVLLRSWYERNKHIFPASRWEPYDPTKSYDKYTI 351
            |||||||:.|.|||:|||||||||||.|||||.:::||:
plant   296 ESHAGKVVERHWYEKNKHIFPASRWEIYDPTKKWERYTV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12259	NP_651595.1	XAP5	110..351	CDD:282738	116/243 (48%)
XCT	NP_179711.2	XAP5	113..334	CDD:398536	116/240 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	242	1.000	Domainoid score	I578
eggNOG	1	0.900	-	-		E1_KOG2894
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3448
Inparanoid	1	1.050	279	1.000	Inparanoid score	I880
OMA	1	1.010	-	-		QHG55025
OrthoDB	1	1.010	-	-		D1061864at2759
OrthoFinder	1	1.000	-	-		FOG0003077
OrthoInspector	1	1.000	-	-		oto3562
orthoMCL	1	0.900	-	-		OOG6_102806
Panther	1	1.100	-	-	LDO	PTHR12722
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2051
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840