DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12259 and Fam50a

DIOPT Version :10

Sequence 1:NP_651595.1 Gene:CG12259 / 43347 FlyBaseID:FBgn0039557 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_613073.2 Gene:Fam50a / 108160 MGIID:1351626 Length:339 Species:Mus musculus


Alignment Length:355 Identity:223/355 - (62%)
Similarity:287/355 - (80%) Gaps:19/355 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAHYKGAASEAGRAAQLMKKREIQQQEIEFRKKKI-EEELKLDKIENKFATHYDAVEQQLKSSTI 64
            ||.|||||||||||..||||||.|::::|..|::| ||.:....|:.||:.||||||.:|||||:
Mouse     1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTV 65

  Fly    65 GLVTLDEMKAKQEDIVREREKKLAQKKDEKDREKQRALEAIQAEKNKQ--KRQIQALSFNLDDDE 127
            |||||::||||||.:|:||||:||:|  |:.:|.|..||.::.::.|:  ||:|.:|||.|:::|
Mouse    66 GLVTLNDMKAKQEALVKEREKQLAKK--EQSKELQLKLEKLREKERKKEAKRKISSLSFTLEEEE 128

  Fly   128 EEEEEDDEDHDKKQLKIKQEDQPKPKWTEIKEDILPIKKKKICKNPDVDTSFLPDREREEQENRL 192
            |..||::|      :.:.:|        |::.:.:..||||:.|||||||||||||:|||:||||
Mouse   129 EGVEEEEE------MAMYEE--------ELEREEITTKKKKLGKNPDVDTSFLPDRDREEEENRL 179

  Fly   193 REQLRQEWVMQQAELKDEDISITFSYWDGSGHRRNVLMKKGNSIYQFLQKCLELLRKEFIELKTV 257
            ||:|||||..:|.::|.|:|.|||||||||||||.|.|||||::.|||||.||:|||:|.||::.
Mouse   180 REELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMKKGNTMQQFLQKALEILRKDFSELRSA 244

  Fly   258 MADQLMYVKEDLILPHHYSFYDFIVTKARGKSGPLFQFDVHDDVRMISDASVEKEESHAGKVLLR 322
            ..:||||:|||||:|||:||||||||||||||||||.||||||||::|||:|||:|||||||:||
Mouse   245 GVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDESHAGKVVLR 309

  Fly   323 SWYERNKHIFPASRWEPYDPTKSYDKYTIK 352
            ||||:|||||||||||||||.|.:|||||:
Mouse   310 SWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12259NP_651595.1 PTZ00121 <5..>199 CDD:173412 103/196 (53%)
XAP5 110..351 CDD:461480 158/242 (65%)
Fam50aNP_613073.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31 21/29 (72%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..177 20/26 (77%)
XAP5 <152..338 CDD:461480 143/185 (77%)
Nuclear localization signal. /evidence=ECO:0000255 152..155 2/2 (100%)

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