DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5003 and AT5G23340

DIOPT Version :9

Sequence 1:	NP_651593.1	Gene:	CG5003 / 43344	FlyBaseID:	FBgn0039554	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_197725.1	Gene:	AT5G23340 / 832398	AraportID:	AT5G23340	Length:	405	Species:	Arabidopsis thaliana

Alignment Length:	414	Identity:	81/414 - (19%)
Similarity:	148/414 - (35%)	Gaps:	125/414 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 EEILG---------RATEKTHTIKICGPPSSQHVAGEFRQ-----FTQTLS-SVFPRVVQLKVLE 174
            :|:.|         ::|::.......||...:.:|..|.|     .:|::| |.:|.|..   .:
plant    28 KEVFGLVCKRWLNLQSTDRKKLAARAGPHMLRRLASRFTQIVELDLSQSISRSFYPGVTD---SD 89

  Fly   175 LEGVSLDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIE--LHLLDLEDLS----IEDNS 233
            |..:|..|::         ||.|.|.:|. .:.||..:   ||.  |.||...|:|    :.|.
plant    90 LAVISEGFKF---------LRVLNLHNCK-GITDTGLA---SIGRCLSLLQFLDVSYCRKLSDK- 140

  Fly   234 WFEPYYIMGLSKLP----SLRRLSLKGCQAL----------------------CKFVPYGSMAAR 272
                    |||.:.    .||.|.|.||:.:                      |..:....:|..
plant   141 --------GLSAVAEGCHDLRALHLAGCRFITDESLKSLSERCRDLEALGLQGCTNITDSGLADL 197

  Fly   273 F-GFQKLESLDLRQ------TPINNSDLQCFSAIENLKELLLESPQILH---SKQAVAKKNTNGN 327
            . |.:|::|||:.:      ..:::....|.|:::.||  ||:..::.:   |..|...||....
plant   198 VKGCRKIKSLDINKCSNVGDAGVSSVAKACASSLKTLK--LLDCYKVGNESISSLAQFCKNLETL 260

  Fly   328 ATDEAASPQPDSLKVLSDDEPSTSRAAMEHLRACKVAFNLDNCSDRKEEKSPVPTEPPSEGQDLQ 392
            ..........:|:.:|:|    :.:.::::||       :|.|.:..:.......:        |
plant   261 IIGGCRDISDESIMLLAD----SCKDSLKNLR-------MDWCLNISDSSLSCILK--------Q 306

  Fly   393 AKRIRAPSESDDEDTSSTSGSSSDKLEVLSLPRNGHSNAAPLS--------------GGVDLPPL 443
            .|.:.|......|:.:.|:.......:||.|.....||...::              ..:|:..|
plant   307 CKNLEALDIGCCEEVTDTAFRDLGSDDVLGLKVLKVSNCTKITVTGIGKLLDKCSSLEYIDVRSL 371

  Fly   444 PHAADAANAADAPIAVDAANIEAP 467
            ||..:        :....|.:|.|
plant   372 PHVTE--------VRCSEAGLEFP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5003	NP_651593.1	F-box	68..114	CDD:279040
CG5003	NP_651593.1	leucine-rich repeat	610..635	CDD:275381
AT5G23340	NP_197725.1	F-box_5	12..48	CDD:408301	3/19 (16%)
		leucine-rich repeat	68..99	CDD:275381	8/33 (24%)
		AMN1	85..323	CDD:187754	56/283 (20%)
		leucine-rich repeat	100..125	CDD:275381	10/28 (36%)
		leucine-rich repeat	126..151	CDD:275381	7/33 (21%)
		leucine-rich repeat	152..177	CDD:275381	6/24 (25%)
		leucine-rich repeat	178..203	CDD:275381	3/24 (13%)
		leucine-rich repeat	204..230	CDD:275381	4/25 (16%)
		leucine-rich repeat	231..256	CDD:275381	6/26 (23%)
		leucine-rich repeat	257..283	CDD:275381	3/29 (10%)
		leucine-rich repeat	284..309	CDD:275381	5/39 (13%)
		leucine-rich repeat	310..336	CDD:275381	4/25 (16%)
		leucine-rich repeat	337..362	CDD:275381	3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010