DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and Fbxl20

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_006534361.1 Gene:Fbxl20 / 72194 MGIID:1919444 Length:438 Species:Mus musculus


Alignment Length:432 Identity:90/432 - (20%)
Similarity:141/432 - (32%) Gaps:149/432 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 ELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRATEKTHTIK 139
            |||..||.:||..::......|..:..|.||...:..|||      .....:|.||..|  :..|
Mouse    33 ELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDL------FDFQRDIEGRVVE--NISK 89

  Fly   140 ICG----PPSSQHVAG----EFRQFTQTLSSVFPRVVQLKVLELEGV--SLDFEYIHITEFPATL 194
            .||    ..|.:...|    ..|.|.|...::       :||.|.|.  :.|.....:::|.:.|
Mouse    90 RCGGFLRKLSLRGCLGVGDNALRTFAQNCRNI-------EVLSLNGCTKTTDATCTSLSKFCSKL 147

  Fly   195 RRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFEPYYIMGLSKL----PSLRRLSLK 255
            |.|.|..|:.....:.|::.....|    ||.|:|   ||.:.....|:..|    ..|:.|.||
Mouse   148 RHLDLASCTSITNMSLKALSEGCPL----LEQLNI---SWCDQVTKDGIQALVRGCGGLKALFLK 205

  Fly   256 GC-----------------------QALCKFVPYGSMAARFGFQKLESLDLRQTPINNSDLQCFS 297
            ||                       |...:....|.:....|..||:||             |.|
Mouse   206 GCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSL-------------CAS 257

  Fly   298 AIENLKELLLES-----PQILHSKQAVAKKNTNGNATDEAAS----------------------- 334
            ...|:.:.:|.:     |::...:.|...:.|:...|..|.:                       
Mouse   258 GCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQL 322

  Fly   335 ----PQ--------------------------PDSLKVLS-DDEPSTSRAAMEHLRACK--VAFN 366
                |:                          .|.|:|:. |:.|..:.|::|||::|.  ....
Mouse   323 SIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIE 387

  Fly   367 LDNC-----SDRKEEKSPVP-----------TEPPSEGQDLQ 392
            |.:|     :..|..::.:|           |.|||.|...|
Mouse   388 LYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQ 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 12/38 (32%)
leucine-rich repeat 610..635 CDD:275381
Fbxl20XP_006534361.1 F-box-like 30..71 CDD:403981 11/37 (30%)
leucine-rich repeat 67..94 CDD:275381 10/34 (29%)
AMN1 95..291 CDD:187754 46/222 (21%)
leucine-rich repeat 95..114 CDD:275381 3/18 (17%)
leucine-rich repeat 121..146 CDD:275381 6/31 (19%)
leucine-rich repeat 147..172 CDD:275381 6/24 (25%)
leucine-rich repeat 173..198 CDD:275381 8/27 (30%)
leucine-rich repeat 199..224 CDD:275381 6/24 (25%)
AMN1 222..396 CDD:187754 29/186 (16%)
leucine-rich repeat 225..250 CDD:275381 3/24 (13%)
leucine-rich repeat 251..276 CDD:275381 7/37 (19%)
leucine-rich repeat 277..302 CDD:275381 4/24 (17%)
leucine-rich repeat 303..328 CDD:275381 0/24 (0%)
leucine-rich repeat 329..357 CDD:275381 0/27 (0%)
leucine-rich repeat 358..382 CDD:275381 9/23 (39%)
leucine-rich repeat 383..408 CDD:275381 3/24 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843139
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1046098at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.850

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