DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and skp2

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_005161246.1 Gene:skp2 / 563708 ZFINID:ZDB-GENE-030219-158 Length:427 Species:Danio rerio


Alignment Length:318 Identity:76/318 - (23%)
Similarity:122/318 - (38%) Gaps:78/318 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 IPTEEEP-EIKQR-----------KREKEHKESL---------DRETECNLMDFC-----DELLF 78
            :.||..| |:.|:           .:.||::|:|         .||:..||   |     ||||.
Zfish    53 LDTENTPNELIQQWSPPHKKALTTAKGKENEENLFVLARRPRKRRESSANL---CWDSLPDELLL 114

  Fly    79 EIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRATEKTHTIKIC-G 142
            .||..|....:|.......|:..|..|...:|.:||.........|.::|.....:......| |
Zfish   115 GIFSRLSLQDLLRTSRVCKRWHRLAFDESLWHSVDLVGKAQLDAELGQVLSAGVLRLRCPHTCIG 179

  Fly   143 PPS--------SQHVAGEFRQF---TQTLSSVFPRVVQLKVLELEGVSLDFEYIHITEFPATLRR 196
            .||        .||:  :|...   |..|..|..|...|:.|.|||:.|....|:.......:.|
Zfish   180 QPSFKSTPSLRVQHL--DFSNCTVETSVLEDVLSRCKHLQNLSLEGLVLSDNIIYSLAQNPEIIR 242

  Fly   197 LKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSW--FEPYYIMGL-SKLPS---------- 248
            |.|..||   |.:|:|:...:.. ...:|::::   ||  |...:|..: |.:||          
Zfish   243 LNLCGCS---GFSPESLTEMLTA-CTRIEEMNV---SWCDFSNLHIQAIASNIPSSVSQLNISGY 300

  Fly   249 LRRLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQTPINNSD----LQCFSAIENL 302
            .:.|:::..:|:.|..|           .:..|||..:.:..:|    ||..|::.:|
Zfish   301 RQNLTMEDVKAIVKRCP-----------NITDLDLSDSVLVTTDSFPVLQQLSSLRHL 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 15/50 (30%)
leucine-rich repeat 610..635 CDD:275381
skp2XP_005161246.1 F-box-like 105..150 CDD:289689 12/44 (27%)
leucine-rich repeat 168..190 CDD:275381 4/21 (19%)
AMN1 190..341 CDD:187754 40/170 (24%)
leucine-rich repeat 191..215 CDD:275381 7/25 (28%)
leucine-rich repeat 216..239 CDD:275381 7/22 (32%)
leucine-rich repeat 240..265 CDD:275381 8/28 (29%)
leucine-rich repeat 266..291 CDD:275381 7/27 (26%)
leucine-rich repeat 292..318 CDD:275381 4/36 (11%)
leucine-rich repeat 319..343 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170587980
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR16134
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.940

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