Protein Alignment CG5003 and Fbxl17

DIOPT Version :9

• Sequence 1: NP_651593.1
• Gene: CG5003 / 43344
• FlyBaseID: FBgn0039554
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_056609.1
• Gene: Fbxl17 / 50758
• MGIID: 1354704
• Length: 701
• Species: Mus musculus
• Alignment Length: 374
• Identity: 74/374 - (19%)
• Similarity: 129/374 - (34%)
• Gaps: 123/374 - (32%)

  Fly     2 EQAELGSTCLAAPKRRFPDNE-RCGRELAAVPVQPVLPQIPTEEEPEIKQRKREKEHKESLDRET 65
            :|.|.|......|    |:|. .|.||             |..|.|:|.|
Mouse   291 QQPESGDADCQEP----PENPCDCHRE-------------PPPEIPDINQ--------------- 323

  Fly    66 ECNLMDFCDELLFEIFQYLDTSS--ILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEIL 128
                  ....:|.:||..|..:.  :.|.:.|. .:.:|.||.:|:..:|||:   ...:.:|:|
Mouse   324 ------LPPSILLKIFSNLSLNERCLSASLVCK-YWRDLCLDFQFWKQLDLSS---RQQVTDELL 378

  Fly   129 GRATEKTHTI--------------KIC-----GPPSSQHVAGEFRQFTQT----LSSVFPRVVQL 170
            .:...::..|              .:|     .|...::.|...:|.:.|    ::|..|.:.::
Mouse   379 EKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKV 443

  Fly   171 KV-----LELEGVSLDFEYIHITEFPATLRRLK---LKDCSVRVGDTPKSIFYSIELHLLDLEDL 227
            .|     |..||         :.:..:..|.||   ...| .::.|....:   |....|.|:.:
Mouse   444 HVGNQDKLTDEG---------LKQLGSRCRELKDIHFGQC-YKISDEGMIV---IAKSCLKLQRI 495

  Fly   228 SIEDNSWFEPYYIMGLSK-LPSLRRLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQ-TPINN 290
            .:::|.......:...:: .|.|:.:...||....|.|.:.:.     .:.|.|||||. |.::|
Mouse   496 YMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTK-----LRNLSSLDLRHITELDN 555

  Fly   291 SDL-----------------------QCFSAI----ENLKELLLESPQI 312
            ..:                       :|...|    :|||||.|.|.:|
Mouse   556 ETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKI 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5003	NP_651593.1	F-box	68..114	CDD:279040	10/47 (21%)
		leucine-rich repeat	610..635	CDD:275381
Fbxl17	NP_056609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..93
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..250
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	279..321		12/46 (26%)
		F-box-like	321..368	CDD:289689	13/68 (19%)
		leucine-rich repeat	362..387	CDD:275381	5/27 (19%)
		leucine-rich repeat	388..413	CDD:275381	2/24 (8%)
		AMN1	411..573	CDD:187754	33/179 (18%)
		leucine-rich repeat	414..439	CDD:275381	4/24 (17%)
		leucine-rich repeat	440..465	CDD:275381	4/33 (12%)
		leucine-rich repeat	466..491	CDD:275381	5/28 (18%)
		leucine-rich repeat	492..517	CDD:275381	2/24 (8%)
		leucine-rich repeat	545..567	CDD:275381	6/21 (29%)
		leucine-rich repeat	568..593	CDD:275381	2/24 (8%)
		leucine-rich repeat	594..618	CDD:275381	7/11 (64%)
		leucine-rich repeat	619..644	CDD:275381
		leucine-rich repeat	645..670	CDD:275381

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843132
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16134
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940