DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5003 and fbxl15

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:NP_998107.1 Gene:fbxl15 / 405878 ZFINID:ZDB-GENE-040426-2440 Length:296 Species:Danio rerio


Alignment Length:346 Identity:66/346 - (19%)
Similarity:114/346 - (32%) Gaps:104/346 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 EEEPEIKQRKREKEHKESLDRETECNLMD--FCDELLFEIFQYLDTSSILAVMHCSPRFENLLLD 105
            :::|:    :|.:.|:        |.|:|  :.|.|:..:|.:|....::::...|..|.:|:  
Zfish     2 DQKPD----ERMQSHR--------CELLDLPWEDVLVSHVFCHLPLRLLVSLQRVSKSFRSLI-- 52

  Fly   106 HRFYHHIDLSNGPLPMGILEEILGRATEKTHTIKICGPPSSQHVAGEFRQFTQTLSSVFPRVVQL 170
                 .:.|.|            .|..:...|    ||...:.......:..|.|.       .|
Zfish    53 -----QVYLDN------------CRTFDPAQT----GPHIPREAFCSILRHNQVLQ-------HL 89

  Fly   171 KVLELEGVSLDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWF 235
            .|........|.:.:.:......|:.:.|:.|:    ...:....::.|....|:.||:....|.
Zfish    90 SVTNCSDWITDTDLLPVIGQNQQLQHVDLRGCA----QLSRRALVAVSLSCPRLQHLSLAHCEWV 150

  Fly   236 EPYYIMGLS-KLPSLRRLSLKGCQAL-----------CKFVPYGSMAARFGF------------Q 276
            :...:..|: ..|.||.|.|..|:.|           |..:...|:|.....            :
Zfish   151 DSLALRSLADHCPMLRSLDLTACRQLKDPAVCYLAGKCPELRALSVAVNANITDTAVEEVAKKCR 215

  Fly   277 KLESLDLRQ-TPINNSDLQCFSAIENLKELL--LESPQILHSKQAVAKKNTNGNATDEAASPQPD 338
            ::|.|||.. ..:.|      .||..|.|..  |:|.::.|..          |.|:       .
Zfish   216 EMERLDLTGCLRVRN------EAIRTLAEYCPKLQSLKVNHCH----------NVTE-------S 257

  Fly   339 SLKVLS------DDEPSTSRA 353
            ||.||.      |.||...||
Zfish   258 SLGVLRRRNVEIDVEPPLQRA 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 9/47 (19%)
leucine-rich repeat 610..635 CDD:275381
fbxl15NP_998107.1 F-box 16..>52 CDD:279040 8/35 (23%)
leucine-rich repeat 51..85 CDD:275381 7/56 (13%)
leucine-rich repeat 86..112 CDD:275381 4/32 (13%)
AMN1 <111..272 CDD:187754 38/187 (20%)
leucine-rich repeat 113..138 CDD:275381 4/28 (14%)
LRR 1 138..159 4/20 (20%)
leucine-rich repeat 139..164 CDD:275381 5/24 (21%)
LRR 2 164..185 6/20 (30%)
leucine-rich repeat 165..190 CDD:275381 7/24 (29%)
LRR 3 190..211 2/20 (10%)
leucine-rich repeat 191..216 CDD:275381 2/24 (8%)
LRR 4 216..237 7/26 (27%)
leucine-rich repeat 217..242 CDD:275381 9/30 (30%)
LRR 5 242..263 8/37 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170588090
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.