DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and Skp2

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster


Alignment Length:257 Identity:61/257 - (23%)
Similarity:104/257 - (40%) Gaps:44/257 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 DELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRATEKTHTI 138
            ||:|.:||::|...::|.:.....||.....|...:..:||....:..|.||:|:.|.   ...|
  Fly   244 DEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLGLRTIRPGALEQIVRRG---VLVI 305

  Fly   139 KICGPPSSQHVAGEFRQFTQ-------------------TLSSVFPRVVQLKVLELEGVSLDFEY 184
            :: ...|.|..|  |..:|:                   :|.::.....|||.:.||.:.||.: 
  Fly   306 RL-AQTSIQEPA--FAPYTEVFRTRLQYLDLSMASITRSSLLTLLSHCRQLKKISLENIELDDD- 366

  Fly   185 IHITEFPATLRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFE------PYYIMGL 243
              |....|....|:..:.::..|.|..|:...:| .|..|..|:|   ||.:      ...:..:
  Fly   367 --ICAEIAKNEALEAVNLTMASGLTSNSVRLMME-SLTSLSSLNI---SWTDLSADAVTALVTHI 425

  Fly   244 SKLPSLRRLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQTPINNSDLQCFSAIENLKEL 305
            |  |:|.||::.||:.    |.:.|..|....:..:.|:|..:..|:......:||...|.|
  Fly   426 S--PNLIRLNIAGCRR----VLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKFKML 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 10/39 (26%)
leucine-rich repeat 610..635 CDD:275381
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 10/39 (26%)
leucine-rich repeat 302..327 CDD:275381 6/27 (22%)
AMN1 309..480 CDD:187754 41/185 (22%)
leucine-rich repeat 328..352 CDD:275381 1/23 (4%)
leucine-rich repeat 353..376 CDD:275381 8/25 (32%)
leucine-rich repeat 377..402 CDD:275381 6/25 (24%)
leucine-rich repeat 403..428 CDD:275381 6/29 (21%)
leucine-rich repeat 429..455 CDD:275381 8/29 (28%)
leucine-rich repeat 456..480 CDD:275381 5/23 (22%)
leucine-rich repeat 481..500 CDD:275381 1/1 (100%)
leucine-rich repeat 506..529 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457993
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR16134
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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