DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and fbxl2

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:NP_956400.1 Gene:fbxl2 / 378737 ZFINID:ZDB-GENE-030925-12 Length:432 Species:Danio rerio


Alignment Length:382 Identity:82/382 - (21%)
Similarity:127/382 - (33%) Gaps:134/382 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 ELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRATEKTHTIK 139
            |||..||.|||..::......|..:..|.||...:..|||.|      ...:|.||..|  :..|
Zfish    27 ELLLRIFSYLDVVTLCRCAQVSKAWNVLALDGSNWQKIDLFN------FQTDIEGRVVE--NISK 83

  Fly   140 ICGPPSSQHVAGEFRQFT---------QTLSSVFPRVVQLKVLELEGVS--LDFEYIHITEFPAT 193
            .||        |..||.:         .::.:.......::.|.|.|.:  .|...|.:::|...
Zfish    84 RCG--------GFLRQLSLRGCLSVGDASMKTFAQNCRNIEHLNLNGCTKITDSTCISLSKFCFK 140

  Fly   194 LRRLKLKDCSVRVGDTPKSIFYSIELHLLD--------LEDLSIEDNSWFEPYYIMGLSKL---- 246
            ||.|.|..|            .||..|.|.        ||:|::   ||.:.....|:..|    
Zfish   141 LRHLDLTSC------------VSITNHALKALSEGCRMLENLNL---SWCDQITSDGIEALSRGC 190

  Fly   247 PSLRRLSLKGC-----------------------QALCKFVPYGSMAARFGFQKLESLDLRQTPI 288
            .:||.|.|:||                       |:..:....|.::...|..||:         
Zfish   191 TALRALFLRGCTQLDDTALKHLQKHCPELMTINMQSCTQITDDGFVSLCRGCHKLQ--------- 246

  Fly   289 NNSDLQCFSAIENLKEL-------------LLESPQILHSKQA---VAKKNTNGN---------- 327
                :.|.|...|:.:.             :||:.:..|...|   |..:|.:..          
Zfish   247 ----MVCISGCSNITDASLTALGLNCQRLKILEAARCSHVTDAGFTVLARNCHEMEKMDLEECIL 307

  Fly   328 ATDEAA------SPQPDSL-----KVLSDD---EPSTSRAAMEHLRACKVAFNLDNC 370
            .||...      .|:..:|     ::::||   ..|:|....|.|:..:    ||||
Zfish   308 VTDNTLVQLSIHCPRLQALSLSHCELITDDGIRHLSSSVCGQERLQVVE----LDNC 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 13/38 (34%)
leucine-rich repeat 610..635 CDD:275381
fbxl2NP_956400.1 F-box-like 24..66 CDD:289689 13/38 (34%)
leucine-rich repeat 61..88 CDD:275381 11/42 (26%)
AMN1 63..284 CDD:187754 53/264 (20%)
leucine-rich repeat 89..108 CDD:275381 2/18 (11%)
leucine-rich repeat 115..140 CDD:275381 6/24 (25%)
leucine-rich repeat 141..166 CDD:275381 9/36 (25%)
leucine-rich repeat 167..192 CDD:275381 7/27 (26%)
leucine-rich repeat 193..218 CDD:275381 6/24 (25%)
AMN1 212..390 CDD:187754 28/166 (17%)
leucine-rich repeat 219..244 CDD:275381 3/24 (13%)
leucine-rich repeat 245..270 CDD:275381 4/37 (11%)
leucine-rich repeat 271..296 CDD:275381 6/24 (25%)
leucine-rich repeat 297..322 CDD:275381 2/24 (8%)
leucine-rich repeat 323..351 CDD:275381 5/27 (19%)
leucine-rich repeat 352..376 CDD:275381 5/13 (38%)
leucine-rich repeat 377..402 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170588067
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1046098at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.850

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