DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and Fbxl2

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_038938600.1 Gene:Fbxl2 / 363156 RGDID:1562243 Length:439 Species:Rattus norvegicus


Alignment Length:608 Identity:114/608 - (18%)
Similarity:181/608 - (29%) Gaps:254/608 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 IFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRATEKTHTIKICGPP 144
            ||.:||..::......|..:..|.||...:..:||.|      ...::.||..|  :..|.||  
  Rat    39 IFSFLDIVTLCRCAQISKAWNILALDGSNWQRVDLFN------FQTDVEGRVVE--NISKRCG-- 93

  Fly   145 SSQHVAGEFRQFTQTLSSVFPRVVQLKVLELEGVSLDFEYIHITEFPATLRRLKLKDCSVRVGDT 209
                                                           ..||:|.|:.| :.|||:
  Rat    94 -----------------------------------------------GFLRKLSLRGC-IGVGDS 110

  Fly   210 PKSIFYSIELHLLDLEDLSIEDNSWFEPYYIMGLSKLPSLRRLSLKGCQALCKFVPYGSMAARFG 274
            ....|                            .....::..|:|.||..:.....|.  .:|| 
  Rat   111 SLKTF----------------------------AQNCRNIEHLNLNGCTKITDSTCYS--LSRF- 144

  Fly   275 FQKLESLDLRQ-TPINNSDLQCFS-AIENLKELLLE-SPQILHSKQAVAKKNTNGNATDEAASPQ 336
            ..||:.|||.. ..:.||.|:..| ...||:.|.|. ..||  :|:.:           ||....
  Rat   145 CSKLKHLDLTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQI--TKEGI-----------EALVRG 196

  Fly   337 PDSLKVL-------SDDEPSTSRAAMEHLR-ACK--VAFNLDNCSDRKEEKSPVPTEPPSEGQDL 391
            ...||.|       .:||      |::|:: .|.  |:.||.:||                    
  Rat   197 CRGLKALLLRGCTQLEDE------ALKHIQNHCHELVSLNLQSCS-------------------- 235

  Fly   392 QAKRIRAPSESDDEDTSSTSGSSSDKLEVLSLPRNGHSN---AAPLSGGVDLPPLP--HAADAAN 451
               ||     :||.......|  ..:|:.|.|  :|.||   |:..:.|::.|.|.  .||..::
  Rat   236 ---RI-----TDDGVVQICRG--CHRLQALCL--SGCSNLTDASLTALGLNCPRLQVLEAARCSH 288

  Fly   452 AADAPIAVDAANIEAPGQSPGLDPRPPRAYIYVPDAENANPRQQRSVVAVFAQGTEQRYIYVNQQ 516
            ..||...:.|.|..                    |.|..:               .:..:.:...
  Rat   289 LTDAGFTLLARNCH--------------------DLEKMD---------------LEECVLITDS 318

  Fly   517 FSLPMNVLMPTRRHRTHPRPNYDQVVQHPMFWNMLEPLDRDYARRVRPRPPSCQTTPQYYVTDRA 581
            ..:.:::..|                       .|:.|...:          |:     .:||..
  Rat   319 TLIQLSIHCP-----------------------KLQALSLSH----------CE-----LITDEG 345

  Fly   582 MYSFGRADRPVQPDVVWIRNINRSP--DNKLERLSLRNYHLITNHTLEHLVQCS--PNLVYIDVS 642
                             |.:::.|.  ..:|..|.|.|..|:|:.:||||..|.  ..|...|..
  Rat   346 -----------------ILHLSSSTCGHERLRVLELDNCLLVTDASLEHLENCRGLERLELYDCQ 393

  Fly   643 GTSITLPAIRRFKISKPKCEVVA 665
              .:|...|:|.:...|:.:|.|
  Rat   394 --QVTRAGIKRMRAQLPRVKVHA 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 8/33 (24%)
leucine-rich repeat 610..635 CDD:275381 11/26 (42%)
Fbxl2XP_038938600.1 F-box-like <38..72 CDD:403981 8/32 (25%)
leucine-rich repeat 68..95 CDD:275381 9/83 (11%)
AMN1 <92..239 CDD:187754 51/274 (19%)
leucine-rich repeat 96..115 CDD:275381 8/19 (42%)
leucine-rich repeat 122..147 CDD:275381 7/27 (26%)
leucine-rich repeat 148..173 CDD:275381 8/24 (33%)
leucine-rich repeat 174..199 CDD:275381 8/37 (22%)
AMN1 184..383 CDD:187754 60/339 (18%)
leucine-rich repeat 200..225 CDD:275381 8/30 (27%)
leucine-rich repeat 226..251 CDD:275381 10/54 (19%)
leucine-rich repeat 252..277 CDD:275381 8/26 (31%)
leucine-rich repeat 278..303 CDD:275381 7/44 (16%)
leucine-rich repeat 304..329 CDD:275381 2/62 (3%)
leucine-rich repeat 330..352 CDD:275381 6/53 (11%)
leucine-rich repeat 359..378 CDD:275381 8/18 (44%)
leucine-rich repeat 384..409 CDD:275381 5/26 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166346644
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1046098at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.850

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