DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5003 and CG9316

DIOPT Version :9

Sequence 1:	NP_651593.1	Gene:	CG5003 / 43344	FlyBaseID:	FBgn0039554	Length:	713	Species:	Drosophila melanogaster
Sequence 2:	NP_610051.2	Gene:	CG9316 / 35333	FlyBaseID:	FBgn0032878	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	84/442 - (19%)
Similarity:	135/442 - (30%)	Gaps:	173/442 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 NLMDFCDELLFEIFQYLDTSSILAVMHC-SPRFENLL-----LDHRFYHHIDLSNGPLPMGILEE 126
            :|:|..::::..:.::|...:...::.| :|:|....     :.......:.|...|||..|
  Fly    41 SLLDLPEDIIRLVLEFLPRITDKVLLACVAPKFRAAFEGWARVQRNALDMVSLETVPLPQLI--- 102

  Fly   127 ILGRATEKTHTIKICGP--------------------------PSSQHVA-----GEFRQFTQTL 160
                     ...|:.||                          |:.:.::     .||.     .
  Fly   103 ---------RFFKVAGPFIRVLQVDCASYQKESLLVEFVKEYCPNLEEISYSNATDEFH-----Y 153

  Fly   161 SSVFPRVVQLKVLELEGVSLD---------------FEYI-------HITEFPATLRRLKLKDC- 202
            .|:..::..||.:.:|.:..:               ||.:       ::..|| .|:.|.|:||
  Fly   154 RSIMSKMTHLKRVTIECLDAEDVLNFDMQPNQELEFFELVNGCYTGQNLCGFP-NLKTLVLRDCL 217

  Fly   203 ---SVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFEPYYIMGLS-------------------- 244
               |:..|...||      ||.|||:|...|         :|.:|
  Fly   218 LWNSMEFGIPLKS------LHTLDLDDCCFE---------VMNVSLYQKIAESCTNLVELIFSGC 267

  Fly   245 --------KLPSLRRLSLKGCQALCKFVPYGSMAARFGF---------QKLESLDLR-QTPINNS 291
                    .||.|.|.:||....        |.....||         .||..|.|. |..|.|.
  Fly   268 DTNFEVIANLPKLERCTLKTWMT--------SNELNIGFLTVLAEKRGNKLTHLHLSGQFNITNE 324

  Fly   292 DLQCFSAIENLKELLLESPQIL---HSK-------------QAVAKKNTNGNATDEAASPQPDSL 340
            ..:|...:.:|.:|...:..||   |.|             .|..:....|........||   |
  Fly   325 HARCLGQLSSLTDLRFSNNDILDDDHFKFFNDLSQLERFGLTACGRVMDVGMMRMLRKCPQ---L 386

  Fly   341 KV--LSDDEPSTSRAAMEHLRACK------VAFNLDNCSDRKEEKSPVPTEP 384
            ||  |:|.|..|....::.:..|.      |..|:.....|:    |:.|.|
  Fly   387 KVIDLTDCEQITEEFVIQAIGFCSKGSGRDVVLNVKGTMIRR----PILTHP 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5003	NP_651593.1	F-box	68..114	CDD:279040	6/51 (12%)
CG5003	NP_651593.1	leucine-rich repeat	610..635	CDD:275381
CG9316	NP_610051.2	leucine-rich repeat	208..221	CDD:275381	5/12 (42%)
		leucine-rich repeat	231..258	CDD:275381	9/35 (26%)
		leucine-rich repeat	259..279	CDD:275381	1/19 (5%)
		leucine-rich repeat	280..309	CDD:275381	7/36 (19%)
		AMN1	310..>411	CDD:187754	25/103 (24%)
		leucine-rich repeat	310..334	CDD:275381	7/23 (30%)
		leucine-rich repeat	335..359	CDD:275381	6/23 (26%)
		leucine-rich repeat	360..385	CDD:275381	2/24 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457951
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930