DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5003 and si:ch73-173p19.1

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_002660968.3 Gene:si:ch73-173p19.1 / 100332407 ZFINID:ZDB-GENE-130530-952 Length:918 Species:Danio rerio


Alignment Length:571 Identity:105/571 - (18%)
Similarity:191/571 - (33%) Gaps:153/571 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 TIKICGPPSSQHVAGEFRQFTQTLSSVFPRVVQL--------KVLELEGVSLDF----EYIHITE 189
            |:.:...||        .|::.:|:.:.|.:.:|        ::|....:.|.|    :...:..
Zfish   471 TVSLMTAPS--------MQYSSSLACLTPELAELLLSHMARERLLRPRTLELFFGCPLQKFVLNC 527

  Fly   190 FPAT----LRRLKLKDCSVRVGDTPKSIFYSIELHLLDLEDLSIEDNSWFEPYYIMGLSKLPSLR 250
            :|.|    ||:|:...|                     |:.||..::.......:..||.|..|:
Zfish   528 YPYTTNELLRQLRAFTC---------------------LKHLSFLNSPLITDAGLSVLSNLSKLQ 571

  Fly   251 RLSLKGCQALCKFVPYGSMAARFGFQKLESLDLRQTPINNSDLQCFSAIENLKELLLESPQILHS 315
            .|:|..|..|..    ..:....|.:.|..|.|.||.::::.|.          |.|:|     .
Zfish   572 HLNLSSCSKLTD----SCLQHITGLRSLTFLALDQTKVSDAGLL----------LYLQS-----G 617

  Fly   316 KQAVAKKNTNGNATDEAASPQPDSLKVLSDDEPSTSRAAMEHLRACKVAFNLDNCSDRKEEKSPV 380
            ..|:.:.:.|..|..|:      :|:||....|.....:::|.:...|:                
Zfish   618 SSALCQLSLNQTAITES------TLRVLPASVPQLRMLSIKHTKVSDVS---------------- 660

  Fly   381 PTEPPSEGQDLQAKRIRAPSESDDEDTSSTSGSSSDKLEVLSLPRNGHSNAAPLSGGVDLPPLPH 445
               ..:|.::||...:            ..:|...:.|:.|:    .|.:.:.||    |..:| 
Zfish   661 ---ALAELKNLQTLHL------------DGTGVQENSLQCLA----SHPSLSALS----LAGIP- 701

  Fly   446 AADAANAADAPIAVDAANIEAPGQ----SPGLDPRPPRAYIYVPDAENANPRQQRSVVAVFAQGT 506
            .||..:..:....:....:..||:    ..||.....:..:...|..:........:..:.:...
Zfish   702 VADGNHTLEIIAGLRLTQLTLPGRHSVTDSGLSFLSRQTLLLELDLTDYTQLTDHGITQLSSMTR 766

  Fly   507 EQRYIYVNQQFSLPMNVLMPTRRHRTHPRPNYDQVVQHPMFWNMLEPLDRDYARRVRPRPPSCQT 571
            .::....|.|.|                    |..:|..:....|:.|..| ...|..|..:...
Zfish   767 LKKLSLSNTQVS--------------------DSGLQGLIRLKELQELCLD-RTAVTSRGVAALI 810

  Fly   572 T--PQYYVTDRAMYSFGRADRPVQPDVVWIRNINRSPDNKLERLSLRNYHLITNHTLEHLVQCSP 634
            |  |...|...|....|        |.|..|.:...|  :|.:|:|.... ||:..|:.|  |..
Zfish   811 THLPHLQVMGLASTQVG--------DTVIRRGLVHCP--QLLKLNLSRTR-ITDQGLKFL--CRM 862

  Fly   635 NLVYIDVSGTSITLPAIRRFKISKPKCEVV-ANHLEEFERLPELETQEEDD 684
            .|..:::.||.:||..|.....:.|....| |:|.....  |:.::.::||
Zfish   863 QLSQVNLDGTGVTLVGIANLISACPHLSSVRASHTRAIP--PDQQSDDDDD 911

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040
leucine-rich repeat 610..635 CDD:275381 8/24 (33%)
si:ch73-173p19.1XP_002660968.3 UBA_like_SF 6..43 CDD:304366
Nop25 116..>169 CDD:286843
UBQ 187..260 CDD:294102
AMN1 523..701 CDD:187754 47/262 (18%)
LRR <524..710 CDD:227223 50/271 (18%)
leucine-rich repeat 545..569 CDD:275381 6/23 (26%)
leucine-rich repeat 570..594 CDD:275381 6/27 (22%)
leucine-rich repeat 595..620 CDD:275381 9/39 (23%)
leucine-rich repeat 621..645 CDD:275381 6/29 (21%)
leucine-rich repeat 646..691 CDD:275381 9/79 (11%)
leucine-rich repeat 692..766 CDD:275381 11/78 (14%)
leucine-rich repeat 717..742 CDD:275381 4/24 (17%)
AMN1 750..>888 CDD:187754 33/171 (19%)
leucine-rich repeat 767..790 CDD:275381 5/42 (12%)
leucine-rich repeat 791..815 CDD:275381 6/24 (25%)
leucine-rich repeat 816..840 CDD:275381 7/33 (21%)
leucine-rich repeat 841..863 CDD:275381 8/24 (33%)
leucine-rich repeat 864..888 CDD:275381 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170588010
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

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