DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5003 and Fbxl13

DIOPT Version :9

Sequence 1:NP_651593.1 Gene:CG5003 / 43344 FlyBaseID:FBgn0039554 Length:713 Species:Drosophila melanogaster
Sequence 2:XP_038962809.1 Gene:Fbxl13 / 100125363 RGDID:1642425 Length:823 Species:Rattus norvegicus


Alignment Length:445 Identity:93/445 - (20%)
Similarity:159/445 - (35%) Gaps:131/445 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 NLMDFCDELLFEIFQYLDTSSILAVMHCSPRFENLLLDHRFYHHIDLSNGPLPMGILEEILGRAT 132
            ||.:.|.:|:     |||.|....:  ....|.|:........|:.:::.|.......::|....
  Rat   404 NLGNGCHKLI-----YLDLSGCTQI--SVQGFRNIANSCTGIMHLTINDMPTLTDNCVKVLVEKC 461

  Fly   133 EKTHTIKICGPPSSQHVA------------------GEFRQFTQTLSSV---FPRVVQLKVLELE 176
            .:..::...|.|   |::                  |..|.......||   :|.:..:.:::.:
  Rat   462 PRISSVVFIGSP---HISDCAFKALSACDLKKIRFEGNKRITDACFKSVDRNYPGISHIYMVDCK 523

  Fly   177 GVS-LDFEYIHITEFPATLRRLKLKDCSVRVGDTPKSIFY----SIELHLLDLEDLS-IEDNSWF 235
            |:: ...:.:.:.:   .|..|.|.:| ||:||.....|:    |::|..|:|.:.| :.|.|  
  Rat   524 GLTDSSLKSLSVLK---QLTVLNLTNC-VRIGDIGLRQFFDGPASVKLRELNLANCSLLGDTS-- 582

  Fly   236 EPYYIMGLS-KLPSLRRLSLKGCQALCKF-VPY-GSMAARFGFQKLESLDLRQTPINNSDLQCFS 297
                ::.|| :.|:|..|:|:.|:.|... :.| .||.:      |.|:||..|.|:|..|...|
  Rat   583 ----VIRLSERCPNLHYLNLRNCEHLTDLAIEYIASMLS------LISIDLSGTLISNEGLAILS 637

  Fly   298 AIENLKE---------------------LLLESPQILHSKQ---------------------AVA 320
            ....|:|                     |.||...:.:..|                     |..
  Rat   638 RHRKLREVSLSECVNITDFGIRAFCKTSLALEHLDVSYCAQLTDDIIKTIAIFCTRITSLHIAGC 702

  Fly   321 KKNTNGNATDEAASPQPDSLKV--------LSDDEPSTSRAAMEHLRACKVAFNLDNCSDRKEEK 377
            .|.|:|..  |..|.:...|.:        |:|......:...:.||..|:.|.....|...::.
  Rat   703 PKITDGGM--EILSARCHYLHILDISGCVQLTDQILQDLQIGCKQLRILKMQFCKSISSAAAQKM 765

  Fly   378 SPVPTE-------PP------SEGQDLQA--KRIRAPSE--------SDDEDTSS 409
            |.|..:       ||      |||..|:.  .:::..||        ||||..:|
  Rat   766 SSVVQQQEYSSESPPSWFGYDSEGNPLEETHTKVKTYSEMIVKESLSSDDETPNS 820

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5003NP_651593.1 F-box 68..114 CDD:279040 11/45 (24%)
leucine-rich repeat 610..635 CDD:275381
Fbxl13XP_038962809.1 Sfi1 <134..>214 CDD:400658
F-box-like 242..286 CDD:403981
leucine-rich repeat 257..270 CDD:275381
leucine-rich repeat 282..308 CDD:275381
AMN1 308..477 CDD:187754 16/82 (20%)
leucine-rich repeat 309..332 CDD:275381
leucine-rich repeat 333..358 CDD:275381
leucine-rich repeat 359..383 CDD:275381
leucine-rich repeat 384..402 CDD:275381
leucine-rich repeat 412..437 CDD:275381 7/31 (23%)
leucine-rich repeat 438..463 CDD:275381 3/24 (13%)
leucine-rich repeat 464..486 CDD:275381 3/24 (13%)
leucine-rich repeat 488..513 CDD:275381 4/24 (17%)
leucine-rich repeat 514..534 CDD:275381 1/19 (5%)
AMN1 525..733 CDD:187754 50/225 (22%)
leucine-rich repeat 539..563 CDD:275381 9/24 (38%)
leucine-rich repeat 567..592 CDD:275381 8/30 (27%)
leucine-rich repeat 593..617 CDD:275381 8/23 (35%)
leucine-rich repeat 618..641 CDD:275381 9/22 (41%)
leucine-rich repeat 642..667 CDD:275381 2/24 (8%)
leucine-rich repeat 668..693 CDD:275381 3/24 (13%)
leucine-rich repeat 694..719 CDD:275381 6/26 (23%)
leucine-rich repeat 720..745 CDD:275381 3/24 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166346668
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.