Protein Alignment Ets98B and SPI1

DIOPT Version :10

• Sequence 1: NP_524535.2
• Gene: Ets98B / 43334
• FlyBaseID: FBgn0005659
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001074016.1
• Gene: SPI1 / 6688
• HGNCID: 11241
• Length: 271
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 71/252 - (28%)
• Similarity: 107/252 - (42%)
• Gaps: 56/252 - (22%)

  Fly   273 SQDPNGWS--PAQVHAWLRSTLAQFRLPPVADLELHFCENGAALALLSEEEFVRRLPESGSTLHA 335
            |...:.|.  |..||:...|                |.||.     .:|.:.|:  |.....|:.
Human    46 SHSDHYWDFHPHHVHSEFES----------------FAENN-----FTELQSVQ--PPQLQQLYR 87

  Fly   336 QLEIWKMAYADQPAHQQHSQQSASTDHWPASYAMPHLDLDY-----NEDSEDDDDMEADAQVAPL 395
            .:|:.:|...|.|....|    .|..| ..|| :|.:.|.|     .:.|.|:::
Human    88 HMELEQMHVLDTPMVPPH----PSLGH-QVSY-LPRMCLQYPSLSPAQPSSDEEE---------- 136

  Fly   396 NGSTTSPPATNASNGGTATVKRPNGGRTGGGGS--HIHLWQFLKELLASPQVNGTAIRWIDRSKG 458
             |...||| ...|:|....::...|...|..||  .|.|:|||.:||.|..:. .:|.|:|:.||
Human   137 -GERQSPP-LEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMK-DSIWWVDKDKG 198

  Fly   459 IFKIEDSVR--VAKLWGRRK-NRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLVYQF 512
            .|:.....:  :|..||.:| ||..|.|.|::|::|.|.|.|.:||.::  :|.|||
Human   199 TFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKK--KLTYQF 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets98B	NP_524535.2	SAM_PNT-PDEF-like	264..345	CDD:188878	15/73 (21%)
		ETS	429..517	CDD:197710	34/87 (39%)
SPI1	NP_001074016.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..165		10/52 (19%)
		Ets	172..253	CDD:459700	31/83 (37%)