DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets98B and spic

DIOPT Version :9

Sequence 1:	NP_524535.2	Gene:	Ets98B / 43334	FlyBaseID:	FBgn0005659	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001004621.1	Gene:	spic / 447882	ZFINID:	ZDB-GENE-040912-47	Length:	263	Species:	Danio rerio

Alignment Length:	198	Identity:	52/198 - (26%)
Similarity:	86/198 - (43%)	Gaps:	40/198 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 SEEEFVRRLPESGSTLHAQLEIWKMAYADQPAHQQHSQQSASTDHWPASYAMPHLDLDYNEDSED 382
            :|.::...|....|::...:..::..        .|.:...||..|..|.:.||
Zfish    30 TENKYYENLDSQQSSVRHAISYYQFT--------PHFEPPGSTYDWNESSSWPH----------- 75

  Fly   383 DDDMEADAQVAPLNGSTTSPPATNASNGGTATVKRPNGGRTGGGGSHIHLWQFLKELLASPQVNG 447
               :..|..:..|..:.||  |..||        .|.  |.|.|...:.|:::|.|.|....: |
Zfish    76 ---VIPDVSLGSLCSTETS--AFYAS--------LPQ--RHGKGRKKLRLYEYLHEALHDDNM-G 124

  Fly   448 TAIRWIDRSKGIFKI--EDSVRVAKLWGRRK-NRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLV 509
            .:|:|.||..|:|..  ::..::|:.||:|| ||..|.|.|::|::|.|.:.|.:.|..|  :|.
Zfish   125 DSIQWTDRGSGVFHFISKNKEKLAECWGQRKGNRKTMTYQKMARALRNYSRTGEIVKVRR--KLT 187

  Fly   510 YQF 512
            |||
Zfish   188 YQF 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets98B	NP_524535.2	SAM_PNT-PDEF-like	264..345	CDD:188878	3/26 (12%)
Ets98B	NP_524535.2	ETS	429..517	CDD:197710	31/87 (36%)
spic	NP_001004621.1	Ets	110..190	CDD:278602	29/82 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3805
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910