DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets98B and spi2

DIOPT Version :9

Sequence 1:	NP_524535.2	Gene:	Ets98B / 43334	FlyBaseID:	FBgn0005659	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_009298595.1	Gene:	spi2 / 103910445	ZFINID:	ZDB-GENE-131121-377	Length:	219	Species:	Danio rerio

Alignment Length:	188	Identity:	51/188 - (27%)
Similarity:	82/188 - (43%)	Gaps:	33/188 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 HQQHSQQSASTDHWPASYAMPHLDLDYNEDSEDDDDMEADAQVAPLNGSTT----SPPATNASNG 410
            ::|.|.:.|..|....|.......:|.:.:...|::     ....::|..|    |.|..|.|:|
Zfish    22 YRQESHRKALWDMTDLSVTSSSGSVDTSAEKRPDEE-----NFIKVSGQETQVMESLPKANISDG 81

  Fly   411 -GTATVKRPN-----------------GGRTGGGGSHIHLWQFLKELLASPQVNGTAIRWIDRSK 457
             |..|:|...                 ...|...|..:.|:.||.|:|..|.: ...:.|:..|.
Zfish    82 RGINTLKAAESPLILHATPEKRVKSLPSSTTAEKGKKLRLFHFLFEMLEDPDM-AHCVSWVPASV 145

  Fly   458 GI--FKIEDSVRVAKLWGRRK-NRPAMNYDKLSRSIRQYYKKGIMKKTERSQRLVYQF 512
            |:  |..::...||:|||:|| ||..|.|.|:||::|.|.:.|.:.|.::  :|.|||
Zfish   146 GVFCFSAKNKEHVAELWGQRKGNRMPMTYQKMSRALRNYSRSGEIIKVKK--KLTYQF 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets98B	NP_524535.2	SAM_PNT-PDEF-like	264..345	CDD:188878
Ets98B	NP_524535.2	ETS	429..517	CDD:197710	32/87 (37%)
spi2	XP_009298595.1	Ets	121..202	CDD:278602	32/84 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3805
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910