Protein Alignment CG12877 and AEN

DIOPT Version :10

• Sequence 1: NP_001034073.1
• Gene: CG12877 / 43333
• FlyBaseID: FBgn0039544
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: XP_054234601.1
• Gene: AEN / 64782
• HGNCID: 25722
• Length: 461
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 67/267 - (25%)
• Similarity: 113/267 - (42%)
• Gaps: 46/267 - (17%)

  Fly   735 RPNRRPNQKERYCSRCGKVFSLDIYEHQSFDMCNYHPKSTGYRRGF--------TDHQHRCCQQP 791
            |..||..|.:|:.:|..      :.:.|........|.|:.....|        .....:|.:..
Human   165 RHKRRSRQHQRFMARKA------LLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAG 223

  Fly   792 AGTPGCTYANYHVSDYYDPEKLTCFVKTIERGEEFVPTKKDIYALDCEMCYT-THG--IELTRVT 853
            :|:..|:                   :....|:...|......|:||||..| ..|  .||.|.:
Human   224 SGSAPCS-------------------RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCS 269

  Fly   854 VVDINGRSVYDALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLE 918
            :|..:|..:||..::|:..|.||.|.:||||...: .:....:..|..::.:...| |:|||:|.
Human   270 IVSYHGDVLYDKYIRPEMPIADYRTRWSGITRQHM-RKAVPFQVAQKEILKLLKGK-VVVGHALH 332

  Fly   919 SDLKALKLIH--DVVVDTSVLFPHKMGPP-----KKRALKTLCIENLKRIIQESEAGHDSAEDAE 976
            :|.:|||.:|  ....||:.: |:.:..|     .:.:||.|.::.|.:.||..:.||.|.|||.
Human   333 NDFQALKYVHPRSQTRDTTYV-PNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDAT 396

  Fly   977 VCIQLIK 983
            ..::|.:
Human   397 TAMELYR 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	PTZ00121	<128..490	CDD:173412
		PRK05035	<458..>583	CDD:481472
		EloA-BP1	572..734	CDD:464914
		REX1_like	834..983	CDD:99848	52/158 (33%)
AEN	XP_054234601.1	DnaQ_like_exo	247..403	CDD:447876	52/158 (33%)