Protein Alignment CG12877 and zgc:152968

DIOPT Version :10

• Sequence 1: NP_001034073.1
• Gene: CG12877 / 43333
• FlyBaseID: FBgn0039544
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_001314684.2
• Gene: zgc:152968 / 564848
• ZFINID: ZDB-GENE-061013-448
• Length: 1250
• Species: Danio rerio
• Alignment Length: 1313
• Identity: 307/1313 - (23%)
• Similarity: 509/1313 - (38%)
• Gaps: 397/1313 - (30%)

  Fly     1 MLPSTGLFKGFLCPYFDGQDAASCKRPFCHFKHARK----------------------------- 36
            |.|||.||....||:.   .:..|:||:|.:.|::.
Zfish     1 MFPSTALFDEIDCPFL---QSGRCQRPYCLYNHSKDSSSDVMNTKGLGDPKVTSANGSFHTTEDN 62

  Fly    37 ----DELE----------AAPPAEPSPVPKYKPAPKLL--------------SLPLPQ------- 66
                :|||          :....|...:.:|:.:..|.              |.|..|
Zfish    63 YACLEELERINKEIEAVRSEVEKEQKRLSQYQTSQSLTQTGQCSGKYLRTTKSRPKDQNGNHLKS 127

  Fly    67 -ITLCA----------PRKKSNLEYHP----EKPALDASPAKKKQEAS--VD--------SAPKY 106
             ..:|:          .|.|::|||.|    ....|.:|.|:.|.::|  ||        ...|.
Zfish   128 KKPVCSTSGQKYVVDRARPKTDLEYDPCSNFSADLLSSSSAECKLKSSDKVDIDHGLKSKQTGKI 192

  Fly   107 VPGQPSVTNGEEYDDWQAVL----------EKEIDEQMQVEIEEQV------QNND--------- 146
            |  ||..::.::.:|...::          .|...:|....|:..|      .|||
Zfish   193 V--QPLSSHFDDSEDKGTLVIDIPSLTKDHRKHKPKQESAIIKTHVLERNGAVNNDLSNQQTNPN 255

  Fly   147 --EEQKIDTVAENE-----EDQENTQ-------LTDARDSHEKD----------------RKPSK 181
              :|:..|.:..::     .||||.:       :|:.::|.|.:                ::.:|
Zfish   256 QHKEKSSDGLPSHDMKCTLSDQENARTLVKPMMITEEQESSEGELVIDVSQFEDEHKLPQQRETK 320

  Fly   182 ERE-------------------------------------RDIEKKKIRELKREKIKDRDRDRDR 209
            .:|                                     :||| ..:.:|:.|.:.:.:...:.
Zfish   321 NKELLDLPKLCPISNAPAEHYKEANDGQIIKGITMANHPGKDIE-PFLEDLREEPVAEPNNFTNI 384

  Fly   210 DRE---KDKEKSKERDREKEKNDRD---KRKSSHSDKER-------------------------- 242
            :.|   |.||: |..:.|...:|..   ....|.||:.:
Zfish   385 NMETFVKQKEE-KAHNLENVLDDISTCLNNMRSQSDELKTIQDVKMLPVNSVYGDECISSQFPRS 448

  Fly   243 ------SKERNTSSSSSSKHKSSSSSSS-------------SKKSSSSDKHR--DDKSSSSRHKS 286
                  |:|...||.|....||.:.||.             |.:|..|..|:  :.:.....|..
Zfish   449 ALQNLTSREPQNSSISGYALKSENVSSKDISQIHQQYFPMVSSQSLPSPLHKAEEHRFLGPPHTQ 513

  Fly   287 SSSSSS----SKSH-----HH--------------KSSSSSSRSKTKRS------SSSSKSAGTS 322
            |.:.:|    ..||     |:              ..|:|....:|..|      |:.|.||...
Zfish   514 SLTETSWVTLQSSHGEPFVHNTPAYVSEIDFGVVSAPSNSQLNPRTVESIEKLPTSNVSYSAACD 578

  Fly   323 KSEPEADKDTEAAVLTPAEPMDDLDDMDFDF-EADTSEGEIVRQCEMIFDEMEKKFAQMHKDEGG 386
            .:.|.....|.|........:|...|.:..: :.|.|:.:.:.:|..||.|
Zfish   579 MTVPSQTFATMAGNNNEPIVVDSSSDAELRYSDLDLSDTDPMEECYRIFME-------------- 629

  Fly   387 NANPESSRKRKAPSPD-IDTFTEAATAALQKRRVAH----ENADK-----ITPHLAPSAAMRKPN 441
             ||...:...:..:|| :.|..::...||.|:||||    |.|.|     |.|....::.:..|:
Zfish   630 -ANQSEAPVVQCDAPDKVGTEMKSNPVALLKKRVAHVAKFEPASKSKAQIIVPLQEGTSHLNVPS 693

  Fly   442 HVRNAMQAIFNRRAEL--RRQEKLQAE---ASAEQVRQAQERVRQAQ-EELRQAKVNSNLTPLIS 500
                        |::|  ||...|.|.   ..::.:..|.::|..:. .::.|:.|.::...:|.
Zfish   694 ------------RSQLCQRRAAILTAAVKGCQSQVINSAPKKVYTSNVHQIHQSAVQNSCVGIIP 746

  Fly   501 RSA----------LTPPVRSARSIAPVANIVAIARAKK-----KIEELQAEKKPA-FTPA----- 544
            ..|          :.|....|..:..:...:::.|..:     ::...|...:|| :|||
Zfish   747 VGATLQLGTNLHFIVPEGNCALPLTLIPTTMSVQRPPQPSPPVQLAPAQHPTQPANYTPAKRQAI 811

  Fly   545 ---------QSFKGAGRVAHKPTAALDKAAPVSNAEKPTVLDPS---------SSKISYNVRIQY 591
                     |.||     .|:|:.|.:.|.    ..:|.|:...         .:|:.::||.:|
Zfish   812 CLSTQDSTQQRFK-----YHRPSEAQNSAL----HSQPNVMGVKRKAKVHHEVGAKVPHDVRQRY 867

  Fly   592 YEMMVRHCTVIYPQLADAWERAQVEELTVFKKCNTPAIYKNSCMLAINKLRKEALEAGNKPSVAC 656
            ..:.|.........:.||:|:|..||..|:.:......|.:..:.|:.:|:.:.:.....||...
Zfish   868 VNLFVEEFLKSSVTVQDAFEKALAEEKIVYDRSINKLKYLSIAVNALKRLKNQNILPAKAPSERD 932

  Fly   657 KTVSHEMMLGGKRALTTSWSVEKKGKLSSLGNGEPFDALDAEKAYKMVFDLRLTEEQLVENGYPR 721
            :.||.     |...|.|. :::..|.|:               .::.:.:..|:|:.|..|.:||
Zfish   933 QHVSR-----GNVPLNTQ-ALQGPGDLT---------------LFEQLKEHILSEDLLQVNNFPR 976

  Fly   722 P-GDKRGSAVIRACRPNRRPNQKERYCSRCGKVFSLD-IYEHQSFDMCNYHPKSTGYRR--GFTD 782
            . .||...|:..........:..:|.|.|||..||:| ..:|...:.||||.......|  |..:
Zfish   977 KHQDKADFAIQYGDTKKGISDPLKRICCRCGATFSVDRSGKHTRREECNYHYGKVIENRVPGGVE 1041

  Fly   783 HQHRCCQQPAGTPGCTYANYHVSDYYDPEKLTCFVKTIER---GEEFVPTKKDIYALDCEMCYTT 844
            .::.||:...|:|||...|.||   :|...|..||.::.:   |:    |...|||:|.:.||||
Zfish  1042 TRYSCCENAVGSPGCQVFNLHV---HDAVSLQGFVSSLHQSAVGK----TCPGIYAIDTQTCYTT 1099

  Fly   845 HGIELTRVTVVDINGRSVYDALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAK 909
            .|:||.|||||..:.:.|:|:.|||||.::||||.:|||:||.:.:.:.::|||||||:|..:|.
Zfish  1100 QGLELARVTVVSSSLQVVFDSFVKPDNDVIDYNTRFSGISEADVKSSSSSLRDVQAVLLSFINAD 1164

  Fly   910 TVLVGHSLESDLKALKLIHDVVVDTSVLFPHKMGPPKKRALKTLCIENLKRIIQESEAGHDSAED 974
            |:|:||.||:||.|||:||..||||||:|||::|.|.||.|.:|..:.|:||||||..|||:.||
Zfish  1165 TILIGHGLENDLAALKIIHSTVVDTSVVFPHRLGLPHKRELNSLTADYLRRIIQESVEGHDTRED 1229

  Fly   975 AEVCIQLIKYYLR 987
            |..|::|:.:.::
Zfish  1230 ATACMELMLWRVK 1242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	PTZ00121	<128..490	CDD:173412	98/542 (18%)
		PRK05035	<458..>583	CDD:481472	28/167 (17%)
		EloA-BP1	572..734	CDD:464914	35/171 (20%)
		REX1_like	834..983	CDD:99848	83/148 (56%)
zgc:152968	NP_001314684.2	None