DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12877 and CG3165

DIOPT Version :9

Sequence 1:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_001285571.1	Gene:	CG3165 / 33503	FlyBaseID:	FBgn0031484	Length:	351	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	44/194 - (22%)
Similarity:	68/194 - (35%)	Gaps:	67/194 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PSPV------------PKYKPAPKLLSLPLPQITLCAPRKKSNLEYHPEKPALDASPAKKKQEAS 99
            ||||            |..:.|.:.|::.|||...|
  Fly   125 PSPVCLVAHNGWGFDFPILRQAFEKLNIELPQSLTC----------------------------- 160

  Fly   100 VDSAPKYVPGQPSVTNGEEYDDWQAVLEKEIDEQMQV--EIEEQVQNNDEEQKIDTVAENEEDQE 162
            |||...::          |.||.|   :|| ..|::|  :::|.:.....:|..:|..:..|...
  Fly   161 VDSLRAFM----------EIDDTQ---QKE-TSQLKVPNDVQEIIPELKPKQNTETCLKEPEAVV 211

  Fly   163 NTQLTDARDSHEKDRKPSKERERDIEKKKIRELKREKIKDRDRDRDRDREKDKEKSKE-RDREK 225
            |   .|.|..:|  ..|:    |.|.|......||:.::|.|.|...::...|.|..| |.|.:
  Fly   212 N---IDWRTRNE--TTPN----RPILKPTEAFAKRKLLRDGDEDDLEEQTPPKRKPDEFRSRRQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821	17/71 (24%)
		EloA-BP1	572..736	CDD:292495
		REX1_like	834..983	CDD:99848
		DnaQ	847..>991	CDD:223916
CG3165	NP_001285571.1	DnaQ	19..>155	CDD:223916	7/29 (24%)
CG3165	NP_001285571.1	TREX1_2	20..173	CDD:99839	16/86 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900