DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12877 and Rexo4

DIOPT Version :9

Sequence 1:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_001029056.1	Gene:	Rexo4 / 311826	RGDID:	1306220	Length:	409	Species:	Rattus norvegicus

Alignment Length:	381	Identity:	89/381 - (23%)
Similarity:	142/381 - (37%)	Gaps:	99/381 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   637 AINKLRKEALEAGNKPSVA--CKTVSHEMMLGGKRALTTSWSVEKKGKLSSLGNGEPFDALDAEK 699
            |:.:|.|...||..||.::  ...:.|::             ::|..|.:|          |..|
  Rat    63 ALQELLKRKSEAPEKPRISQLDDKIHHQI-------------IQKNRKKTS----------DKSK 104

  Fly   700 AYKMVFDLRLTEEQLVENGYPRPGDKRGSAVIRACRPNRRPNQKERYCSRCGKVFSLDIYEHQSF 764
            ..|...|.:.|.:.:  ...|:...|.......|....::...::|..|        |:..||.
  Rat   105 GDKRTEDDKPTRDSV--TSAPKKVRKTPVPPTNASGTEQKKGAEKRTRS--------DLSSHQG- 158

  Fly   765 DMCNYHPKSTGYRRGFTDHQHR--------CCQQPAGTPGCTYANYHVSDYYDPEKLTCFV---- 817
                             |.:|:        ...||..|....:     .|..||:.:...|
  Rat   159 -----------------DIKHKGKAKEAAVILSQPTPTEEDIW-----FDDVDPDDIEAAVGPEA 201

  Fly   818 -----KTIERGEEFVPTKKD--------IYALDCEMC-YTTHGIE--LTRVTVVDINGRSVYDAL 866
                 |.:.:....:...|:        ..||||||. ....|.|  ..||::|:..|:.|||..
  Rat   202 AMLVRKRLGQRTSTISLVKEQAFGGLTKALALDCEMVGVGPKGEESIAARVSIVNQYGKCVYDKY 266

  Fly   867 VKPDNQIVDYNTTYSGITEAML--SNETRTI-RDVQAVLMSMFHAKTVLVGHSLESDLKALKLIH 928
            |||...:.||.|..|||....|  ..|...: ::|.|:|..     .:||||:|.:|||.|.|.|
  Rat   267 VKPTEPVTDYRTAVSGIRPENLKQGEEFEVVKKEVAAMLKG-----RILVGHALRNDLKVLFLEH 326

  Fly   929 --DVVVDTSVLFPHK-MGPPKKRALKTLCIENLKRIIQESEAGHDSAEDAEVCIQL 981
              ..:.||....|.: :....:.:||.|..:.|...:|::|  |.|.:||:..::|
  Rat   327 PKKKIRDTQKFKPFRSLVKSARPSLKQLSEKILGLRVQQAE--HCSVQDAQAAMRL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821
		EloA-BP1	572..736	CDD:292495	19/100 (19%)
		REX1_like	834..983	CDD:99848	54/157 (34%)
		DnaQ	847..>991	CDD:223916	47/143 (33%)
Rexo4	NP_001029056.1	DnaQ	228..>392	CDD:223916	54/160 (34%)
Rexo4	NP_001029056.1	REX4_like	231..381	CDD:99847	54/157 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810