Protein Alignment CG12877 and prage

DIOPT Version :10

• Sequence 1: NP_001034073.1
• Gene: CG12877 / 43333
• FlyBaseID: FBgn0039544
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_001188528.1
• Gene: prage / 31136
• FlyBaseID: FBgn0283741
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 850
• Identity: 194/850 - (22%)
• Similarity: 347/850 - (40%)
• Gaps: 212/850 - (24%)

  Fly   239 DKERSKERNTSSSSSSKHKSSSSSSSSKKSSSSDK------------------HRDDKSSSSRHK 285
            ||.:|..:|:||..::.:.:.:::|:...:||:.:                  ::...::..::.
  Fly   109 DKMQSCNKNSSSRITTTNNNVTTTSNISGNSSNKRCPQKYTGNTLAVNSNMLAYQQQATAGGKNS 173

  Fly   286 SSSSSSSSKSHHHKSSSSSSRSKTKRSSSSSKSAGTSKSEPEADKDTEAAVLTPAEPMDDLDDMD 350
            :..|..::...:|:......:.:.......:.:||.:.||           .:||.|..:.
  Fly   174 TRKSRHNNNKQNHQQQQQQQQQQFDHIHKRNGTAGGTGSE-----------CSPAAPTSNW---- 223

  Fly   351 FDFEADTSEGEIVRQCEMIFDEMEKKFAQMHKDEGGNANPESSRKRKAPSPDIDTFTEAATAALQ 415
              .:.......:...|      :|.|....|..  |:.|..||   .|.|.|||:.:|     |.
  Fly   224 --LQRGYGRQFVHSSC------IEDKLLGHHNP--GHRNSTSS---DATSEDIDSSSE-----LP 270

  Fly   416 KRRVAHENADKITPHLAPSAAMRKPNHVRNAMQAIFNRRAELRR---------QEKLQAEASAEQ 471
            .:...:..|..|  |.:..:..|...|.:.:.|...|.....:|         |:..|..|...|
  Fly   271 NKSKGNSCAGSI--HASGGSKSRSKRHQKQSGQQTRNPDHNGQRTGAATPCTGQKAKQGNAKWRQ 333

  Fly   472 VR---QAQERVRQAQEELRQAKVNSNLTPLISRSALTPPVRSARSIAPVANIVAIARAKKKIEEL 533
            .:   .:..:.:|.|::::|.|...|
  Fly   334 QQPNPSSNNQQQQMQQQMQQQKRGRN--------------------------------------- 359

  Fly   534 QAEKKPAFTPAQSFKGAGRVAHKP-----------------TAALDKAAPVSNAEKPTVLDPSSS 581
               |||.       |.:..:...|                 ::||  ::|.|:|.......|::|
  Fly   360 ---KKPG-------KWSNNIIDNPNSNHGGSSQQKTCDSSSSSAL--SSPTSSATTSATSSPTNS 412

  Fly   582 KISY------NVRIQ-------YYEMMVRHCTVIYPQLADAWERAQVEELTVFKKCNTPAIYKNS 633
            ..||      ..||:       ..|:..::...:.|.|.. :|:.:.::.||.::.....|  ::
  Fly   413 PTSYPRANGNRKRIEAALEWRREQELGRQNANFLVPPLRQ-YEQLEFDDKTVVQQLRRHII--DN 474

  Fly   634 CMLAI------NKLRKEALEAGNKPSVACKTVSHEMMLGG----KRALT--------TSWSVEKK 680
            .:|.:      :.:.:.|:|       ..|.:.|......    .:|:|        |:.:.|:.
  Fly   475 HLLRVYGFPVDSVVHEGAIE-------IFKCMPHMSFAAALAETAQAVTVINYHDGLTNRAEEEV 532

  Fly   681 GKLSSLGNGEPFDALDAEKAYKMVFDLRLTEEQLVENGYPRPGDKRGSAVIRACR--PNRRPNQK 743
            ...:..||..| .:||:|..    .:...:|.:...:.....|:......::.|.  |..|...|
  Fly   533 ANSTDSGNSSP-QSLDSESG----GEWSGSECESSNSSSSSAGEAALGLELKYCHFVPVERSLSK 592

  Fly   744 ERYCSRCGKVFSLD--IYEHQSFDMCNYHPKSTGYRRGFTDHQH---RCCQQ-PAGTPGCTYANY 802
            .  |:||.:.|.:|  ..::.:.:.|.||  |..|:|.:....|   .||.: ...:|||...:.
  Fly   593 P--CARCKRHFLVDELTGQYLTHEECQYH--SGKYQRYYDGVSHGRWTCCNEGEESSPGCCLGDR 653

  Fly   803 HV---------SDYYDPEKLTCFVKTIERGE-EFVPTKKDIYALDCEMCYTTHGIELTRVTVVDI 857
            ||         ..|||      ||:|..||. |..|.   :|||||||.||..|:::|:|::|.:
  Fly   654 HVWSGSVVGVNGPYYD------FVRTEHRGSGEDEPA---VYALDCEMSYTGRGLDVTKVSLVAL 709

  Fly   858 NGRSVYDALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDLK 922
            ||:.||:..|:|...|:||||.||||||..|.:..:::.:||..|:.:..|.|:|:||.||:||:
  Fly   710 NGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLR 774

  Fly   923 ALKLIHDVVVDTSVLFPHKMGPPKKRALKTLCIENLKRIIQ--ESEAGHDSAEDAEVCIQLIKYY 985
            ||:|:|:.::|||:.|||..|.|.:|||:.|...:|||.||  :...||.|.||:..|::|:.:.
  Fly   775 ALRLVHNTLIDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMELMLWR 839

  Fly   986 LRNKI 990
            :..::
  Fly   840 VNREL 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	PTZ00121	<128..490	CDD:173412	48/280 (17%)
		PRK05035	<458..>583	CDD:481472	22/153 (14%)
		EloA-BP1	572..734	CDD:464914	30/192 (16%)
		REX1_like	834..983	CDD:99848	71/150 (47%)
prage	NP_001188528.1	PH-like	<614..650	CDD:473070	12/37 (32%)
		REX1_like	686..837	CDD:99848	71/150 (47%)