DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12877 and SPAC637.09

DIOPT Version :9

Sequence 1:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_594627.2	Gene:	SPAC637.09 / 2543505	PomBaseID:	SPAC637.09	Length:	631	Species:	Schizosaccharomyces pombe

Alignment Length:	186	Identity:	80/186 - (43%)
Similarity:	109/186 - (58%)	Gaps:	16/186 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   819 TIERGEEFV---------------PTKKDIYALDCEMCYTTHGIELTRVTVVDINGRSVYDALVK 868
            |:.:|||..               |....|.|:||||..|.:|:|:.|||:||:....:||..||
pombe   247 TVMKGEEVTQPSGWVASAGDFHSPPINPKILAIDCEMVRTENGLEIARVTIVDMKSEVIYDEFVK 311

  Fly   869 PDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDLKALKLIHDVVVD 933
            |::.:.||.|.||||||..|.|.|..:.|||:.|.......|||:||||.|||..||..|..::|
pombe   312 PESPVTDYVTQYSGITEEKLRNVTTVLSDVQSYLKKTVDNNTVLLGHSLNSDLNCLKFTHPHIID 376

  Fly   934 TSVLFPHKMGPPKKRALKTLCIENLKRIIQESEA-GHDSAEDAEVCIQLIKYYLRN 988
            |:.::.|..|||.|.:||.|..:.|:|.||::.| ||||||||..|:.|:|..::|
pombe   377 TANIYNHTRGPPSKPSLKWLATKWLRREIQKAGALGHDSAEDALACVDLLKLKVKN 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821
		EloA-BP1	572..736	CDD:292495
		REX1_like	834..983	CDD:99848	72/149 (48%)
		DnaQ	847..>991	CDD:223916	67/143 (47%)
SPAC637.09	NP_594627.2	DnaQ	272..532	CDD:223916	75/161 (47%)
SPAC637.09	NP_594627.2	REX1_like	277..427	CDD:99848	72/149 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	143	1.000	Domainoid score	I1173
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47103
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2254
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940