DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12877 and C05C8.5

DIOPT Version :9

Sequence 1:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	NP_504838.1	Gene:	C05C8.5 / 179116	WormBaseID:	WBGene00015462	Length:	594	Species:	Caenorhabditis elegans

Alignment Length:	192	Identity:	74/192 - (38%)
Similarity:	102/192 - (53%)	Gaps:	22/192 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   816 FVKTIER---------GEE-FVPTKK---------DIYALDCEMCYT-THGIELTRVTVVDINGR 860
            ||.|.|:         ||| .||||:         .::::|||||.| ....||||:::||....
Worm   185 FVLTTEQLAQRRYPFPGEEGVVPTKQGYKKISASSPMFSVDCEMCETDVANRELTRISIVDEFEN 249

  Fly   861 SVYDALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDLKALK 925
            ::.|.||||:.:|.||.|.:||||..|:...|.|:.|||..:.|:.....:|||||||.||:|:|
Worm   250 TILDTLVKPEGRITDYVTRWSGITPDMMEGVTTTLGDVQKAIQSLLPPDAILVGHSLEHDLQAMK 314

  Fly   926 LIHDVVVDTS-VLFPHKMGPPKKRALKTLCIENLKRIIQESEAGHDSAEDAEVCIQLIKYYL 986
            :.|...:|.. ||.........:.:||.|....|...|| ||.||.|.|||...::|.:..|
Worm   315 MTHPFCLDVGHVLNYTNSNTEFRNSLKNLTELFLGAQIQ-SEFGHCSYEDAWAAMRLAQLKL 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821
		EloA-BP1	572..736	CDD:292495
		REX1_like	834..983	CDD:99848	62/150 (41%)
		DnaQ	847..>991	CDD:223916	57/141 (40%)
C05C8.5	NP_504838.1	REX1_like	222..372	CDD:99848	62/150 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12801
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910