Protein Alignment CG12877 and pqe-1

DIOPT Version :9

• Sequence 1: NP_001034073.1
• Gene: CG12877 / 43333
• FlyBaseID: FBgn0039544
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_498135.2
• Gene: pqe-1 / 175731
• WormBaseID: WBGene00004095
• Length: 1647
• Species: Caenorhabditis elegans
• Alignment Length: 1167
• Identity: 270/1167 - (23%)
• Similarity: 452/1167 - (38%)
• Gaps: 326/1167 - (27%)

  Fly    40 EAAPPAEPSPV-----PKYKPA---PKLLSLPLPQITLC----------------------APRK 74
            |..||...|||     .|.:|.   |::..:| ||:.:.                      |||:
 Worm   576 EPPPPCSYSPVAQSSESKIEPVDVKPRVAPVP-PQVPVTPTKPVITNNKKKRIDVVTLDEDAPRR 639

  Fly    75 KSNLEYHPEKPAL------DASPAKK-----KQEASVDSAPKYVPGQPSVTNGEEYDDWQAVLEK 128
            ....:..||..:.      ||:|..:     |||...|.||..:     :.:.::::..:|..|.
 Worm   640 VQVKQEIPEVSSTSDATKSDAAPTARGAVRIKQEVESDVAPNTI-----LISAKKFERMKAEAED 699

  Fly   129 EIDEQMQV-EIEEQVQNNDEEQKID-------------------------TVAENEED------- 160
            :.|.:.:: .::|.:.|..||::::                         .|:.:|.|
 Worm   700 KEDMKKKIAALQEALFNIQEERRVEKEIAAFATTNQAVPQNQPASSVQIAQVSTSESDAPGTSEA 764

  Fly   161 ----------QENTQLTDARDSHEKDR-----KPSKER-----ERDIEKKKIRELKREKIKDRDR 205
                      .:|..:.:.....|:|.     |.||:|     ..|.|::.:|..||...:.|::
 Worm   765 AATETMTSPKTKNNVIVETEGEQEEDEDEIPIKKSKKRRAKIVSNDEEEEPVRHPKRRSDEKREK 829

  Fly   206 ------------------------------------DRDRD------------------------ 210
                                                |.|.|
 Worm   830 RHVSYAESDDDMPVVKKKRRNQSPEDPEYSAASPSEDEDDDIGSFVVSDNEDDDADSFVVGDDEP 894

  Fly   211 ---REKDKEKSKER--DREKEKNDRDKRKSSHSDKERSKERNT------SSSSSSKHKSSSS--- 261
               .|:|::...||  .|::..:.|.|:.::.:|:.||::..|      |:|.:.:.||..:
 Worm   895 IEYEEEDEDDMIERRSSRKRRSDSRSKKSATPTDRRRSRDTPTGSRSMRSTSPNDRRKSRETPPG 959

  Fly   262 SSSSKKSSSSD--KHRDDKSSSSRHKSSSSSSSSKS----------HHHKSSSSSSRSKTKRSSS 314
            :.|.:::|.||  |.||..::||...||:.|...||          ...|.:......||:..:.
 Worm   960 NRSMRRTSPSDGRKSRDTPTASSSMSSSTLSYCKKSKETPMSYEEIEQQKKAKRQRNCKTREENR 1024

  Fly   315 SSKSAGTSKSEPEADKDTEAAVLTPAEPMDDLDDMDFDFEADTSEGEIVRQCEMIFDEMEKKFAQ 379
            ..|.  .::.|.....:|.....|.....|:.|.:|........|          |.:.:||.|:
 Worm  1025 ERKR--LAQLEELESSETTGVRRTLRSTQDNSDPLDASLATTIEE----------FRKTKKKDAK 1077

  Fly   380 MHKDEGGNANPESSRKRKAPSPDIDTFTEAATAALQKRRVAHENADKITPHLAPSAAMRKPNHVR 444
            ..::. .....:...||...|..:|:..:.  ..:..:|:||.::       .|..:..||..:
 Worm  1078 SSENR-AKEKQKPMNKRPTSSASVDSNDDG--VHIPAKRMAHASS-------VPGPSRSKPPMI- 1131

  Fly   445 NAMQAIFNR--RAELRRQEKLQAEASAEQVRQAQERVRQ-----AQEELRQAKVNSNLTPLISRS 502
               .|:.||  ..|:..:...::|....:.|...||:|.     .:|:::.|::.:.|..:...:
 Worm  1132 ---GAVKNRPNHTEMLDKRNKESEEKRRKDRDELERLRNKKHTTEEEKIKMARLQNALKVVGKAA 1193

  Fly   503 ALTPPVRSARSIAPVANIVAIARAKKKIEELQAEKKPAFTPAQSFKGAGRVAHKPTAALDKAAPV 567
            .|.                  |..||::....|:|:                 ||..|:.|....
 Worm  1194 GLK------------------ATVKKELTGSPAKKQ-----------------KPAPAVPKILDF 1223

  Fly   568 SNAEKPTVLDPSSSKISYNVRIQYYEMMVRHCTVIYPQLADAWERAQVEELTVFKKCNTPAIYKN 632
            |.....|.:..::.|:.::             |.:.....:|...||..||::.|:......|:.
 Worm  1224 SVGRTFTAIRQTAIKLVFD-------------TFLERDSPNAAREAQEFELSIAKQYTDGQKYRI 1275

  Fly   633 SCMLAINKLRKE----ALEAGNKPSVACKTVSHEMMLGG--KRALTTSWSVEKKGKLSSLGNGEP 691
            :....:..||||    .||. ||     ..|||:.:|.|  |...|.:     :|:.:.:.:.:
 Worm  1276 NIGHKVAALRKENTSGILEV-NK-----NAVSHDKILAGGPKDNCTVA-----RGRKTHVDHRQ- 1328

  Fly   692 FDALDAEKAYKMVFDLRLTEEQLVENGYPRPGDKRGSAVIRACRPNRRPNQK--------ERYCS 748
               |..||.:.::...:||..:|..|.||...|....||..|.....: |:|        .|.||
 Worm  1329 ---LSIEKLHPLLLQFKLTTSELETNAYPMRRDGSTKAVSIADTVYTQ-NKKMFLDDYDMSRNCS 1389

  Fly   749 RCGKVFSLD-----IYEHQSFDMCNYHPKS---TGYRRGFTDHQHRCCQQPAGTP-GCTYANYHV 804
            ||.|.|.|.     |   :|..:|.||.:.   .|.|..|. .::.||.:..... ||.:::.||
 Worm  1390 RCNKEFKLSPNGTMI---RSTGICRYHNRGVAINGKRDTFR-KRYSCCNEEFNVALGCKFSDVHV 1450

  Fly   805 SDYYDPEKLTCFVKTIERGEEFVPTKKD-----IYALDCEMCYTTHGIELTRVTVVDINGRSVYD 864
            :|....::|:.||.|.      ||...|     :|||||||.||..|..|.|:|:||:....|.|
 Worm  1451 TDQLFKKELSTFVSTP------VPVPNDQRSTRVYALDCEMVYTIAGPALARLTMVDMQRNRVLD 1509

  Fly   865 ALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDLKALKLIHD 929
            ..|||...::|.||.:||:|...:::...|::.....|....:|.|:|:||||||||||::::|.
 Worm  1510 VFVKPPTDVLDPNTEFSGLTMEQINSAPDTLKTCHQKLFKYVNADTILIGHSLESDLKAMRVVHK 1574

  Fly   930 VVVDTSVLFPHKMGPPKKRALKTLCIENLKRIIQ---ESEAGHDSAEDAEVCIQLIKYYLRN 988
            .|:||::||  :.....|.|||.|..:.|.:.||   |...||||.|||..|:.||.|.|||
 Worm  1575 NVIDTAILF--RSTRDTKVALKVLSAKLLHKNIQGDNEDAIGHDSMEDALTCVDLIFYGLRN 1634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821	20/122 (16%)
		EloA-BP1	572..736	CDD:292495	39/169 (23%)
		REX1_like	834..983	CDD:99848	65/151 (43%)
		DnaQ	847..>991	CDD:223916	60/145 (41%)
pqe-1	NP_498135.2	PHA03160	<285..405	CDD:165431
		Amelogenin	<377..502	CDD:197891
		EloA-BP1	1230..1364	CDD:292495	36/161 (22%)
		REX1_like	1479..1629	CDD:99848	65/151 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166930
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	211	1.000	Inparanoid score	I2370
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D774159at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4760
orthoMCL	1	0.900	-	-		OOG6_103246
Panther	1	1.100	-	-	LDO	PTHR12801
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2254
SonicParanoid	1	1.000	-	-		X1541
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.930