Protein Alignment CG12877 and Pan2

DIOPT Version :10

• Sequence 1: NP_001034073.1
• Gene: CG12877 / 43333
• FlyBaseID: FBgn0039544
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: XP_006513048.1
• Gene: Pan2 / 103135
• MGIID: 1918984
• Length: 1205
• Species: Mus musculus
• Alignment Length: 485
• Identity: 113/485 - (23%)
• Similarity: 182/485 - (37%)
• Gaps: 116/485 - (23%)

  Fly   569 NAEK--PTVLDPSSSKISYNVRIQYYEMMVRHCTVIYPQLADAWERAQVEELTVFKKCNTPAIYK 631
            |.||  ||:.       :.|:| ...:::|.:|.|...:.||.| |.|.|  ..||
Mouse   720 NCEKYQPTIQ-------TRNIR-HLPDILVINCEVNSSKEADFW-RLQAE--VAFK--------- 764

  Fly   632 NSCMLAINKLRKE------AL----EAGNKPSVACKTV----------SHEMMLGGKRAL-TTSW 675
                :|:.|...|      ||    |..:.....|.::          |..|.:...:.| ..:|
Mouse   765 ----IAVKKYGGEMKSKEFALADRKELRSPEGFLCSSIEELKNVWLPFSIRMKMTKNKGLDVCNW 825

  Fly   676 SVEKKGKLSSLGNGEPFDALDAEKAYKM-VFDLRLTEEQLVENGYPRPGDKRGSAVIRACRPNRR 739
            :.|.  :|||||....:....||:...: |:||..|...::::       :.|.:::...:....
Mouse   826 ADEH--ELSSLGAPSQWGPARAEEELGVYVYDLMATVVHILDS-------RTGGSLVAHIKVGET 881

  Fly   740 PNQKER-------YCSRCGKVFSLDIYEHQSFDMCNYHPKSTGY--RRGFTDHQHRCCQQPAGTP 795
            .:|::.       |......:..:|.||...||| |:...:..|  :|......:...:.|
Mouse   882 YHQRKEGVTHQQWYLFNDFLIEPIDKYEAVQFDM-NWKVPAILYYVKRNLNSRYNLNIKNP---- 941

  Fly   796 GCTYANYHVSDYYDPEKL----TCFVKTIERGEEFVPTKKDIYALDCEMCY------------TT 844
              ..|:..:::.....|.    |.|:..:...   :|...|:..||.|...            |.
Mouse   942 --IEASVLLAEASLARKQRKTHTTFIPLMLNE---MPQVGDLVGLDAEFVTLNEEEAELRSDGTK 1001

  Fly   845 HGIELTRVTVVDI---------NGRSVYDALVKPDNQIVDYNTTYSGITEAML-----SNETRTI 895
            ..|:.::::|..|         .|....|..:....|:|||.|.||||....|     |....|:
Mouse  1002 STIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTL 1066

  Fly   896 RDVQAVLMSMFHAKTVLVGHSLESDLKALKLI--HDVVVDTSVLFPHKMGPPKKR--ALKTLCIE 956
            :.....|..:.......|||.|:.|.:.:.|:  .|.|:||..|| |.   |:||  :|:.|...
Mouse  1067 KSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLF-HM---PRKRMISLRFLAWY 1127

  Fly   957 NLKRIIQESEAGHDSAEDAEVCIQLIKYYL 986
            .|...||...  |||.|||...:||.:.||
Mouse  1128 FLDLKIQGET--HDSIEDARTALQLYRKYL 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	PTZ00121	<128..490	CDD:173412
		PRK05035	<458..>583	CDD:481472	5/15 (33%)
		EloA-BP1	572..734	CDD:464914	40/185 (22%)
		REX1_like	834..983	CDD:99848	51/178 (29%)
Pan2	XP_006513048.1	WD40	75..357	CDD:475233
		UCH_1	516..902	CDD:463872	44/214 (21%)
		PAN2_exo	979..1152	CDD:99846	51/178 (29%)