DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12877 and rexo4

DIOPT Version :9

Sequence 1:	NP_001034073.1	Gene:	CG12877 / 43333	FlyBaseID:	FBgn0039544	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	XP_002665913.1	Gene:	rexo4 / 100333127	ZFINID:	ZDB-GENE-050411-124	Length:	418	Species:	Danio rerio

Alignment Length:	323	Identity:	83/323 - (25%)
Similarity:	135/323 - (41%)	Gaps:	49/323 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   676 SVEKKGKLSSLGNGEPFDALDAEKAYKMVFDL---------RLTEEQLVENGYPRPGDKRGSAVI 731
            :|..|.|.||     |.|:...||.:|...:.         |:.::..:.||..:.|.|:..|..
Zfish    93 NVNGKQKPSS-----PKDSHKPEKRFKKAKETVKAESEKSKRVEKDGELTNGKEQSGHKQFKAEK 152

  Fly   732 RACRPNRRP--NQKERYCSRCGKVFSLDIYEHQSFDMCNYHPKSTGYRRGFTDHQHRCCQQPAGT 794
            |..:..:..  |:|.:......|....|::    ||..:.....:.......|...:.|    |.
Zfish   153 RKNKDGKEKGMNKKSKAEEEEKKTAEPDLW----FDDVDPDDIESALGTEAADIMRKRC----GL 209

  Fly   795 PGCTYANYHVSDYYDPEKLTCFVKTIERGEEFVPTKKDIYALDCEMC---YTTHGIELTRVTVVD 856
            ..|           ||:...   |.:.:...|....:.: |:||||.   |......|.||::|:
Zfish   210 AKC-----------DPKNTE---KMLVKEHAFEGVTRAV-AMDCEMVGVGYKGEDSILARVSLVN 259

  Fly   857 INGRSVYDALVKPDNQIVDYNTTYSGITEAMLSNETRTIRDVQAVLMSMFHAKTVLVGHSLESDL 921
            ..|:.:||..|||..::.||.|..|||....:.| ...|:.||..:..:...: :||||::.:||
Zfish   260 HFGKCIYDKYVKPTEKVTDYRTAVSGIRPDDIKN-GEDIKTVQKEVAQILKGR-ILVGHAIHNDL 322

  Fly   922 KALKLIH--DVVVDTSVLFPHKMGPPKKR-ALKTLCIENLKRIIQESEAGHDSAEDAEVCIQL 981
            |.|.|.|  .::.||....|.:......| ||:.||.:.|...:|:.|  |.|.:||:..::|
Zfish   323 KILLLDHPKKMIRDTQRYKPFRQKVKSSRPALRNLCRQILNVQVQQGE--HSSVQDAQATMRL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12877	NP_001034073.1	CDC45	129..>199	CDD:280821
		EloA-BP1	572..736	CDD:292495	17/68 (25%)
		REX1_like	834..983	CDD:99848	52/154 (34%)
		DnaQ	847..>991	CDD:223916	46/138 (33%)
rexo4	XP_002665913.1	DnaQ	231..>384	CDD:223916	52/158 (33%)
rexo4	XP_002665913.1	REX4_like	234..385	CDD:99847	52/155 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810