DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CROT and Crot

DIOPT Version :9

Sequence 1:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	XP_038964380.1	Gene:	Crot / 83842	RGDID:	70908	Length:	752	Species:	Rattus norvegicus

Alignment Length:	618	Identity:	199/618 - (32%)
Similarity:	329/618 - (53%)	Gaps:	55/618 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRA 77
            ::.||.:.::||.||:|.|.:::::|...::||..::|..:..:.:.:||:|||..||::|.:||
  Rat   150 EERTFQYQDSLPPLPVPSLEESLKKYLESVKPFANEDEYKKTEEIVQKFQDGVGKTLHQKLLERA 214

  Fly    78 AGMRNWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARH----------I 132
            .|.||||..||.:..|..:|          :||||.:..|..:|.:.....||.          :
  Rat   215 KGKRNWLEEWWLNVAYLDVR----------IPSQLNVNFVGPSPHFEHYWPAREGTQLERGSILL 269

  Fly   133 HHSLEFWDLTR-------KSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDE 190
            .|:|.:|.|.|       ||...||..|         .::..||||:|||..:|.|..:|.|:.|
  Rat   270 WHNLNYWQLLRREKLPVHKSGNTPLDMN---------QFRMLFSTCKVPGITRDSIMNYFKTESE 325

  Fly   191 GKTPSHMLISGKGRQFIFDCVHEDDTILSAPEILVALQRVRSILDYEPLGDCVPTLSHDERSTWA 255
            |..|:|:.:..:||.|:||.:| |..:::.||:|..|..:......||:|..:..|:.:||:.||
  Rat   326 GHCPTHIAVLCRGRAFVFDVLH-DGCLITPPELLRQLTYIYQKCWNEPVGPSIAALTSEERTRWA 389

  Fly   256 RNRNRLREISVANKETLLLVESACMEICWY-------EQSPKDYEESCQLGLYGDLHSRWADRSS 313
            :.|..|..:   :.|.|.|:|.....:..|       ..:|:::.:..::.|.||...||.|:|.
  Rat   390 KAREYLIGL---DPENLTLLEKIQSSLFVYSIEDTSPHATPENFSQVFEMLLGGDPAVRWGDKSY 451

  Fly   314 SIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFLEVPEPDWAEAEKGNVLEV-KELHFQLDDT 377
            ::|:|.||....:.:|:.||..|.::.|.::....||. |..|..:||...:.: :||.|.:|:.
  Rat   452 NLISFANGIFGCSCDHAPYDAMVMVNIAHYVDEKLLET-EGRWKGSEKVRDIPLPEELAFTVDEK 515

  Fly   378 LKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYE 442
            :.|::.:.:........|:.:..:.|..:||...|...||||:|:|:.:|.|||::|......||
  Rat   516 ILNDVYQAKAQHLKAASDLQIAASTFTSFGKKLTKKEALHPDTFIQLALQLAYYRLHGRPGCCYE 580

  Fly   443 TALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVD---EHKHFMNEARKGHG 504
            ||:.|.:|:|||||:||||   .|.:|...:.|....||....::.:|   :|...|.:...|.|
  Rat   581 TAMTRYFYHGRTETVRSCT---VEAVRWCQSMQDPSASLLERQQKMLDAFAKHNKMMRDCSHGKG 642

  Fly   505 IDRHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTANVGFVAPMVFDGYGVFY 569
            .||||.||...|.|..:.:|..::||::::||||||||||:|.:|:....|.|.|||.:|||.||
  Rat   643 FDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRIQGVVVPMVHNGYGFFY 707

  Fly   570 SITSEAVFINTTAYRDSLKTSARKFNDIFKDSF 602
            .|..:...:..:::|..|:|.|.|..::...:|
  Rat   708 HIRDDRFVVTCSSWRSCLETDAEKLVEMIFHAF 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
Crot	XP_038964380.1	Carn_acyltransf	160..743	CDD:395612	197/608 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353003
Domainoid	1	1.000	341	1.000	Domainoid score	I1051
eggNOG	1	0.900	-	-		E1_KOG3718
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10899
Inparanoid	1	1.050	349	1.000	Inparanoid score	I2218
OMA	1	1.010	-	-		QHG49249
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0006330
OrthoInspector	1	1.000	-	-		oto96351
orthoMCL	1	0.900	-	-		OOG6_107213
Panther	1	1.100	-	-	LDO	PTHR22589
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4606
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770