Protein Alignment CROT and Cpt1c

DIOPT Version :9

• Sequence 1: NP_001334704.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_001344599.1
• Gene: Cpt1c / 78070
• MGIID: 2446526
• Length: 799
• Species: Mus musculus
• Alignment Length: 652
• Identity: 168/652 - (25%)
• Similarity: 275/652 - (42%)
• Gaps: 116/652 - (17%)

  Fly    17 FDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEF--QNGVGAQLHEQLKKRAAG 79
            |.|...||..|:|..::|:.:|...::|....:...:|....::|  .:....||:.|||.....
Mouse   165 FSFQRALPRQPVPSAQETVRKYLESVRPVLGDDAFDRATALANDFLRLHAPRLQLYLQLKSWCTS 229

  Fly    80 MRNWLGTWWEDYGYHLIRMPLL--PYQLM-----VMPSQLEMVGVPETPEYMLKSLARHIHHSLE 137
              |::..|||::.|...|..|:  .|.:|     |.|:.|:..........:|  |.||:.:..|
Mouse   230 --NYVSDWWEEFVYLRSRGSLINSTYYMMQDFLYVTPTPLQAARAGNAVHTLL--LYRHLLNRQE 290

  Fly   138 FWDLTRKSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGK 202
            . ..|....::||         .||.|:..|:|.|:||.|:||: :|.      :...|:.:..:
Mouse   291 I-SPTLLMGMRPL---------CSAQYERMFNTTRIPGVEKDHL-RHL------QDSRHVAVFHR 338

  Fly   203 GRQFIFDCVHEDDTILSAPEILVALQRVRSILDYE----PLGDCVPTLSHDERSTWARNRNRLRE 263
            ||.|... .|..:.:|| |..|.  |:.:.|||..    ||.:.:..|:...||.||:.|..::.
Mouse   339 GRFFRVG-THSPNGLLS-PRALE--QQFQDILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKT 399

  Fly   264 ISVANKETLLLVESACMEICWYEQSPKDY---EESCQLGLY------GDLHSRWADRSSSIIAFR 319
            .:....|.   ||.|...:. .:..|...   :.:..|..|      |..|.||.|:|.::|.|.
Mouse   400 HAATALEA---VEGAAFFVS-LDSEPAGLTREDPAASLDAYAHALLAGRGHDRWFDKSFTLIVFS 460

  Fly   320 NGRCNWTGEHSCYDGTVS-----ISYAT-FMQLSFLE------VPEPDWAEAEKGNVLEVKELHF 372
            ||:...:.|||..|..||     .:.|| ..||.:..      .|:|...:.::        |.:
Mouse   461 NGKLGLSVEHSWADCPVSGHLWEFTLATECFQLGYATDGHCKGHPDPTLPQPQR--------LQW 517

  Fly   373 QLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEI 437
            .|.:.::..|....:.......::......|..:||.|:|...:..|||:|:|:|.|:::...:.
Mouse   518 DLPEQIQPSISLALRGAKTLSGNIDCHVFPFSHFGKSFIKCCHVSSDSFIQLVLQLAHFRDRGQF 582

  Fly   438 APTYETALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKG 502
            ..|||:|:.|.:..|||||:||||....:|:||..||:.....|| .||.|||:|:..:..|..|
Mouse   583 CLTYESAMTRLFLEGRTETVRSCTREACQFVRAMDNKETDQHCLA-LFRVAVDKHQALLKAAMSG 646

  Fly   503 HGIDRHLFGLWCAAYESKMDIPAF-------------------------YDDPMYTKSGGGGNFV 542
            .|||||||.|:..:....|..|..                         ::.|.|..||||
Mouse   647 QGIDRHLFALYIMSRLLHMQSPFLTQVQSQQWLLSTSQVPVQQTHLIDVHNYPDYVSSGGG---- 707

  Fly   543 LSSSTLGFTANVGFVAPMVFDGYGVFYSITSE-AVFINTTAYRDSLKTSARKFNDIFKDSFRRIS 606
                          ..|....|||:.|....| |:..:.::.:.|.:|.:.:.....:::...::
Mouse   708 --------------FGPAHDHGYGISYIFMGENAITFHISSKKSSTETDSHRLGQHIENALLDVA 758

  Fly   607 VL 608
            .|
Mouse   759 SL 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
Cpt1c	NP_001344599.1	CPT_N	1..46	CDD:318644
		Carn_acyltransf	171..754	CDD:307070	165/638 (26%)
		Coenzyme A binding. /evidence=ECO:0000250	552..564		4/11 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920