Protein Alignment CROT and CROT

DIOPT Version :9

• Sequence 1: NP_001334704.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_001137407.1
• Gene: CROT / 54677
• HGNCID: 2366
• Length: 640
• Species: Homo sapiens
• Alignment Length: 645
• Identity: 195/645 - (30%)
• Similarity: 326/645 - (50%)
• Gaps: 79/645 - (12%)

  Fly    13 DKNTFDFDETLPSLPLPELRDTMERYY-----SC-----------------------IQPFGTKE 49
            ::.||.:.::|||||:|.|.:::::|.     :|                       ::||..:|
Human    10 EERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQE 74

  Fly    50 ELAQARKTIDEFQNGVGAQLHEQLKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEM 114
            |..:..:.:.:||:|:|.:||::|.:||.|.||||..||.:..|..:|          :||||.:
Human    75 EYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVR----------IPSQLNV 129

  Fly   115 --VGV--------PETPEYMLKSLARHIHHSLEFWDLTRKSSI-------KPLSSNGGKIKYSSA 162
              .|.        |......|:..:..:.|:|.:|.|.||..:       .||..|
Human   130 NFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMN--------- 185

  Fly   163 LYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFDCVHEDDTILSAPEILVAL 227
            .::..||||:|||..:|.|..:|.|:.||::|:|:::..:||.|:||.:|| ..:::.||:|..|
Human   186 QFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHE-GCLVTPPELLRQL 249

  Fly   228 QRVRSILDYEPLGDCVPTLSHDERSTWARNRNRLREISVANKETLLLVESACMEICWYEQS---- 288
            ..:......||.|..:..|:.:||:.||:.|..|..:...|...|..::|:.:.....:.|
Human   250 TYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVT 314

  Fly   289 PKDYEESCQLGLYGDLHSRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFLEVPE 353
            |:||.|.....|.||...||.|:|.::|:|.||......:|:.:|..:.::.:.::.....: .|
Human   315 PEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQ-NE 378

  Fly   354 PDWAEAEKGNVLEV-KELHFQLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLH 417
            ..|..:||...:.: :||.|.:|:.:.|:|.:.:........|:.:...||..:||...|...||
Human   379 GRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLH 443

  Fly   418 PDSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLA 482
            ||:|:|:.:|.|||::|......||||:.|.:|:|||||:||||.....:.::..:..|......
Human   444 PDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQ 508

  Fly   483 RAFRRAVDEHKHFMNEARKGHGIDRHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSST 547
            :...:|..:|...|.:...|.|.||||.||...|.|..:.:|..:.||:::|||||||||||:|.
Human   509 QKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSL 573

  Fly   548 LGFTANVGFVAPMVFDGYGVFYSITSEAVFINTTAYRDSLKTSARK--------FNDIFK 599
            :|:....|.|.|||.:|||.||.|..:...:..:|::...:|.|.|        |:|:.:
Human   574 VGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQ 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
CROT	NP_001137407.1	Carn_acyltransf	20..631	CDD:279140	193/635 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158998
Domainoid	1	1.000	342	1.000	Domainoid score	I1078
eggNOG	1	0.900	-	-		E1_KOG3718
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10899
Inparanoid	1	1.050	350	1.000	Inparanoid score	I2284
Isobase	1	0.950	-	0	Normalized mean entropy	S2491
OMA	1	1.010	-	-		QHG49249
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0006330
OrthoInspector	1	1.000	-	-		oto89227
orthoMCL	1	0.900	-	-		OOG6_107213
Panther	1	1.100	-	-	LDO	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4606
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720