Protein Alignment CROT and ChAT

DIOPT Version :9

• Sequence 1: NP_001334704.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_477004.5
• Gene: ChAT / 42249
• FlyBaseID: FBgn0000303
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 689
• Identity: 174/689 - (25%)
• Similarity: 292/689 - (42%)
• Gaps: 125/689 - (18%)

  Fly     7 YFMSKDDKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQ--NGVGAQL 69
            :..:.:..:.|.|.:|||.:|:|.|.:||..|...::|..|..:|.:.::.|.:|.  .|:||:|
  Fly    72 WLSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARL 136

  Fly    70 HEQLKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQL---MVMPSQLEMVGVPETPEYMLKSLARH 131
            |:.|..:.....||...:|.:..|..||:| ||...   ||.|.: ....|.:...:..:.|...
  Fly   137 HQYLLDKREAEDNWAYYYWLNEMYMDIRIP-LPINSNPGMVFPPR-RFKTVHDVAHFAARLLDGI 199

  Fly   132 IHHSLEFWDLTRKSSIKPLSSNGGKIK---YSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKT 193
            :.|. |..|    |...||.....:.|   ...|.|.....:||.||.:||   ..||
  Fly   200 LSHR-EMLD----SGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQD---SQFL------- 249

  Fly   194 PSHMLISGKGRQFIFDCVHE---------DDTILSAPEILVALQRVRSILDYEPLGDCVPT---- 245
            ||...::.:.|..:..|.::         |...||..||   ..::..:|...|   |:|.
  Fly   250 PSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEI---ASQILYVLSDAP---CLPAKPVP 308

  Fly   246 ---LSHDERSTWARNRNRLREISVANKETLLLVESACMEICWYEQSPKDYEESCQLGLYGDLH-- 305
               |:.:.||||||:|..|:| ...|:..|.|:|:|.:.:|..|....::......|....:|
  Fly   309 VGLLTAEPRSTWARDREMLQE-DERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRA 372

  Fly   306 -----------------------SRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLS 347
                                   :||.|::..:|...:|......||||.:|   |:....::..
  Fly   373 GDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEG---IAVVQLLEKI 434

  Fly   348 FLEVPE-PDWAEAEKGNVL--------EVKELHF--QLDDTLKNEIKRVQKDIDDRGIDVTVTFT 401
            :.::.| ||     :.|.|        |..|.|.  ||........|.|.|.|||  :|..|  .
  Fly   435 YKKIEEHPD-----EDNGLPQHHLPPPERLEWHVGPQLQLRFAQASKSVDKCIDD--LDFYV--Y 490

  Fly   402 AFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTETLRSCTSAVAE 466
            .:..|||.|:|:.::.||.::|:.:|.|:|:::..:..|||:|..|::.:||.:.:|:.::...|
  Fly   491 RYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAASTEALE 555

  Fly   467 FLRA-----------SSNKQVGDMS------------LARAFRRAVDEHKHFMNEARKGHGIDRH 508
            :.:|           .|:::..:.|            |...||.||......|.:...|:|||..
  Fly   556 WAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKNILGNGIDIP 620

  Fly   509 LFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTAN--VGFVAPMVFDGYGVFYSI 571
            |.||..|:.|...::...:.|..|..|   ..|:||:|.:..:.:  :|: .|:...|||..|:.
  Fly   621 LLGLREASIEVTGEMHELFKDESYIIS---QCFLLSTSQVACSTDSFMGY-GPVTPRGYGCSYNP 681

  Fly   572 TSEAVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLE 610
            ..|.:....:|:.....|||.::....:||...:..||:
  Fly   682 HPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLLQ 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
ChAT	NP_477004.5	Carn_acyltransf	88..716	CDD:279140	169/667 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950