DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CROT and cpt2

DIOPT Version :9

Sequence 1:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_989193.1	Gene:	cpt2 / 394801	XenbaseID:	XB-GENE-963400	Length:	658	Species:	Xenopus tropicalis

Alignment Length:	648	Identity:	174/648 - (26%)
Similarity:	278/648 - (42%)	Gaps:	106/648 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TFDFDETLPSLPLPELRDTMERYYSCIQP------FGTKEELAQARKTIDEFQNGVGAQLHEQLK 74
            |..|.::||.||:|:|.||::||.:..:|      |...|:||.      .||||||.||||:|.
Frog    43 TMHFQKSLPRLPIPKLEDTIKRYLNAQRPLLDDVQFKKTEQLAL------NFQNGVGKQLHEELV 101

  Fly    75 KRAAGMRNW---LGTWWE-------------------------DYGYHLIRMPLLPYQLM----- 106
            ::....::.   .|.|::                         ||...|||...:....|
Frog   102 QQDKQNKHTSYISGPWFDMYLCARESIVLNFNPFISFTPDPRPDYNRQLIRATNMTVSAMRFLKT 166

  Fly   107 ----VMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTRKSSIKPLSSNGGKIKYSSALYKHF 167
                .:..::..:...::.....:.|.|.:..||. |......:..||         ..:.|...
Frog   167 MRAGYLEPEIFHLNPAKSDTLTFRKLIRFVPSSLS-WYGAYMVNAYPL---------DMSQYFRL 221

  Fly   168 FSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFDCVHEDDTILSAPEILVALQRVRS 232
            |:..|:|...:|.:    .|.::|:   |:|:..||..::||.:.:|..|:.|.||...||.:
Frog   222 FNGTRIPKPNRDEL----WTDEKGR---HLLVLRKGNFYVFDVIDKDGNIVKASEIQAHLQHI-- 277

  Fly   233 ILDYEPLGDCVPT-------LSHDERSTWARNRNRLREISVANKETLLLVESACMEICWYEQSPK 290
                  |.|..|.       |:.:||:|||..|.:|  ::..|:|.|..|:||...:|..:...:
Frog   278 ------LSDTTPAPEFPLGYLTSEERNTWAVLRQKL--LNNGNQEALAKVDSAVFCLCLDDFPVE 334

  Fly   291 DYEESCQLGLYGDLHSRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFLEVP--E 353
            |........|:|...:||.|:|.|||...:|......|||..||...:.:...:.....:.|  .
Frog   335 DRVSLSHNMLHGSGLNRWFDKSFSIIMTEDGTAAVNFEHSWGDGVAVLRFQNEVFKDSTQRPAIS 399

  Fly   354 PDWAEAEKGNVLEVKELHFQLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHP 418
            |:...|...:...|:.|||.|||:||..|...::..|.....:::....|...||:.:||.:|.|
Frog   400 PESCSAPVDSSKAVQRLHFNLDDSLKAAIANAKEKFDTSVNALSIATMEFKKGGKELLKTQKLSP 464

  Fly   419 DSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTETLR-------SCTSAVAEFLRASSNKQV 476
            |:..|:..|.|:.:.:.:...|||:.....:.:|||||:|       .|:.|   |:...|....
Frog   465 DAVSQLSFQMAFLRQYGKTTATYESCSTAAFKHGRTETVRPASIYTKKCSEA---FVMHPSKHSP 526

  Fly   477 GDMSLARAFRRAVDEHKHFMNEARKGHGIDRHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNF 541
            .:  |....:.....|.....||..|.|.|||||.|...|....:.:|..|.|..|.:.   .:.
Frog   527 AE--LRSMLQDCSKYHGQLTKEAAMGQGFDRHLFALRYLASSKGLSLPEIYQDASYAQI---NHN 586

  Fly   542 VLSSSTLGFTA-NVGFVAPMVFDGYGVFYSITSEAVFINTTAY-----RDSLKTSARKFNDIF 598
            |||:|||...| .:|..||:|.||:||.|.:..:.:..|.::|     |..::...:..:|||
Frog   587 VLSTSTLTSPAVQLGGFAPVVPDGFGVGYGVHDDWIGCNVSSYQTRDVRQFVECVHQSLDDIF 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
cpt2	NP_989193.1	Carn_acyltransf	50..649	CDD:376382	170/639 (27%)
cpt2	NP_989193.1	Coenzyme A binding. /evidence=ECO:0000250	453..465		5/11 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920