DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CROT and whd

DIOPT Version :9

Sequence 1:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001163111.1	Gene:	whd / 36109	FlyBaseID:	FBgn0261862	Length:	782	Species:	Drosophila melanogaster

Alignment Length:	636	Identity:	167/636 - (26%)
Similarity:	262/636 - (41%)	Gaps:	69/636 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMR 81
            :.|..:||.||||.::|||.||...::|....|...:..:...||:..:|.:|...|..::....
  Fly   165 YSFQGSLPRLPLPSVKDTMTRYLRSVRPLLDDENYTRMERLAKEFEQTIGKKLQWYLILKSWWST 229

  Fly    82 NWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTRKSS 146
            |::..|||:|.|...|.||...........:.|    ...:......|..|...|.|..|.....
  Fly   230 NYVSDWWEEYVYLRGRSPLCVNSNFYGTDAIFM----NLTDKQAARAANVISLLLNFRRLIEHQE 290

  Fly   147 IKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHI-----EKHFLTKDEGKTPSHMLISGKGRQF 206
            ::|:... |.|...|..|:..|:|.||||.|.|.|     ..|.:...:| ....|||..|||
  Fly   291 LQPIMVQ-GMIPLCSWQYERTFNTARVPGLETDRIIHYRDSNHIVVLHKG-CYYKMLIYYKGR-- 351

  Fly   207 IFDCVHEDDTILSAPEILVALQRVRSILDYEPLGDCVP--------TLSHDERSTWARNRNRLRE 263
                      ||...|:.|.::.:..       |...|        .|:...||.||..||....
  Fly   352 ----------ILRPCELQVQIEEILK-------GKATPVEGEEHLAALTAWNRSKWAEARNTFFS 399

  Fly   264 ISVANKETLLLVESACMEICWYEQ-------SPKDYEESCQLGLYGDLHSRWADRSSSIIAFRNG 321
            ..| |:.:|..:|||...:...::       .|:..:...:..|:|:.::||.|:..::....||
  Fly   400 WGV-NQTSLRTIESAAFVLSLDDEPFEFDLARPELLDNFGKKLLHGNGYNRWFDKCFTVCVGTNG 463

  Fly   322 RCNWTGEHSCYDGTVSISYATFMQLSFLEVPEPDWAEAEKGNVLEVKELHFQLDDTLKNEIKRVQ 386
            |..:..||:..|..:    |:.|..:.:..........|.||..............|..::|...
  Fly   464 RVGFNAEHTWSDAAI----ASHMWENLIVDDLVSDGYDETGNTKGTPAFQPPTPTRLTWDLKPCL 524

  Fly   387 KDIDDRGIDVT-------VTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETA 444
            ..|::..||||       :......||||.|||..|:.||:::|:.:|.|||:.....:.|||.:
  Fly   525 AQIEEATIDVTKLINEVNLRILVHQDYGKGFMKKCRISPDAYIQMALQLAYYRDAGRFSLTYEAS 589

  Fly   445 LMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHL 509
            :.|.:..|||||:|.||...:.:::|..|....:....:..:.|.|.|:....:|..|.||||||
  Fly   590 MTRLFREGRTETVRPCTIESSAWVKAMQNPNTTNDERVKMMQAACDRHQLGYQDAMCGRGIDRHL 654

  Fly   510 FGLWCAAYESKMDIPAFYDDPM---------YTKSGGGGNFVLSSSTLGFTANVGFVAPMVFDGY 565
            |.|:..:...::|.| |.::.:         .|..|......|.......:|..|| .|:..|||
  Fly   655 FCLYVVSKYLEVDSP-FLNEVLSEPWRLSTSQTPHGQTPKMDLKKHPNCISAGGGF-GPVADDGY 717

  Fly   566 GVFYSITSE-AVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLEQLAKE 615
            ||.|.|..| .:|.:.:|.....:|...:|......:...|..:.||..|:
  Fly   718 GVSYIIAGENLIFFHISAKTTCQQTDVHRFAQNISQALSDIRSMFEQHMKD 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_001334704.1	None
whd	NP_001163111.1	CPT_N	1..45	CDD:293093
whd	NP_001163111.1	Carn_acyltransf	171..759	CDD:279140	162/619 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448722
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35481at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950