Protein Alignment CROT and Cpt1a

DIOPT Version :10

• Sequence 1: NP_733230.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: NP_113747.2
• Gene: Cpt1a / 25757
• RGDID: 2396
• Length: 773
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 174/656 - (26%)
• Similarity: 281/656 - (42%)
• Gaps: 120/656 - (18%)

  Fly    17 FDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMR 81
            :.|..:||.||:|.::||:.||...::|...:|:..:......:|...:|.:|...||.::....
  Rat   165 YSFQTSLPRLPVPAVKDTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWAT 229

  Fly    82 NWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLT-RKS 145
            |::..|||:|.|...|.|     |||..:...|..:..||.::..:.|.:..|::..:..| .:.
  Rat   230 NYVSDWWEEYIYLRGRGP-----LMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDRE 289

  Fly   146 SIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFDC 210
            .:||:...|..|...||.::..|:|.|:||||.|.|: |.      |...|:::..:||.|....
  Rat   290 ELKPIRLLGSTIPLCSAQWERLFNTSRIPGEETDTIQ-HI------KDSRHIVVYHRGRYFKVWL 347

  Fly   211 VHEDDTILSAPEILVALQRVRSILD--YEPL-GDC-VPTLSHDERSTWARNRNRLREISVA---N 268
            .| |..:|...|:   .|:::.|||  .||. |:. :..|:..:|..||    :.|:...|   |
  Rat   348 YH-DGRLLRPREL---EQQMQQILDDPSEPQPGEAKLAALTAADRVPWA----KCRQTYFARGKN 404

  Fly   269 KETLLLVESACM-------EICWYEQSPK----DYEESCQLGLYGDLHSRWADRSSSIIAFRNGR 322
            |::|..||.|..       |..:.|:.|:    .|.:|.   |:|....||.|:|.:.:.|:|.:
  Rat   405 KQSLDAVEKAAFFVTLDESEQGYREEDPEASIDSYAKSL---LHGRCFDRWFDKSITFVVFKNSK 466

  Fly   323 CNWTGEHSCYDGTV------SISYATFMQLSFLE-----------VPEPDWAEAE-KGNVLEVKE 369
            .....|||..|..|      .:......||.:.|           :|:|...:.: .|...||.:
  Rat   467 IGINAEHSWADAPVVGHLWEYVMATDVFQLGYSEDGHCKGDTNPNIPKPTRLQWDIPGECQEVID 531

  Fly   370 LHFQLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMH 434
            ........|.|              ||.:....||.:||..:|..|..||:|:|:.:|.|:|:..
  Rat   532 ASLSSASLLAN--------------DVDLHSFPFDSFGKGLIKKCRTSPDAFIQLALQLAHYKDM 582

  Fly   435 KEIAPTYETALMRQYYNGRTETLRSCTSAVAEFLRASSN-KQVGDMSLARAFRRAVDEHKHFMNE 498
            .:...|||.::.|.:..|||||:||||.....|::|..: |...:..| :.|:.|.::|:|....
  Rat   583 GKFCLTYEASMTRLFREGRTETVRSCTMESCNFVQAMMDPKSTAEQRL-KLFKIACEKHQHLYRL 646

  Fly   499 ARKGHGIDRHLFGLWCAAYESKMDIP-------------------------AFYDDPMYTKSGGG 538
            |..|.|||||||.|:..:....:|.|                         .|..:|.|...|||
  Rat   647 AMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKNPDYVSCGGG 711

  Fly   539 GNFVLSSSTLGFTANVGFVAPMVFDGYGVFYSITSE-AVFINTTAYRDSLKTSARKFNDIFKDSF 602
                              ..|:..|||||.|.|..| .:..:.::...|.:|.:.:|....:.:.
  Rat   712 ------------------FGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAM 758

  Fly   603 RRISVL 608
            ..|..|
  Rat   759 MDIITL 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_733230.1	Carn_acyltransf	26..594	CDD:459926	168/631 (27%)
Cpt1a	NP_113747.2	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..756	CDD:459926	169/637 (27%)