Protein Alignment CROT and Cpt1b

DIOPT Version :10

• Sequence 1: NP_733230.1
• Gene: CROT / 43332
• FlyBaseID: FBgn0039543
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: XP_006242242.1
• Gene: Cpt1b / 25756
• RGDID: 2397
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 175/659 - (26%)
• Similarity: 281/659 - (42%)
• Gaps: 128/659 - (19%)

  Fly    17 FDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMR 81
            :.|..:||.||:|.:..|:.||...::|....|...:......|||:.:..:|.:.|..::....
  Rat   167 YSFQTSLPKLPVPSVPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWAT 231

  Fly    82 NWLGTWWEDYGYHLIRMPLL---PYQLMVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTR 143
            |::..|||:|.|...|.|::   .|..|      :.|.:..|.:...: |...:|..:.:.....
  Rat   232 NYVSDWWEEYVYLRGRSPIMVNSNYYAM------DFVLIKNTSQQAAR-LGNTVHAMIMYRRKLD 289

  Fly   144 KSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIF 208
            :..|||:.:. |.:...|...:..|:|.|:||:|.|.:: |.   .|.:   |:.:..||| |..
  Rat   290 REEIKPVMAL-GMVPMCSYQMERMFNTTRIPGKETDLLQ-HL---SESR---HVAVYHKGR-FFK 345

  Fly   209 DCVHEDDTILSAPEILVALQRVRSILD----YEPLGDCVPTLSHDERSTWARNRNRLREISVANK 269
            ..::|...:|...::.:..||   |||    .:|..:.:..|:...|..||..|.:... |..||
  Rat   346 VWLYEGSCLLKPRDLEMQFQR---ILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFS-SGKNK 406

  Fly   270 ETLLLVESACMEICWYEQS----PKDYEESCQLG----LYGDLHSRWADRSSSIIAFRNGRCNWT 326
            .:|..:|.|...:...|.|    |.| |.|..|.    |:|:.::||.|:|.::|:.:||:....
  Rat   407 MSLDTIERAAFFVALDEDSHCYNPDD-EASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLN 470

  Fly   327 GEHSCYDGTV-------SISYATFMQLSFLE----VPEPD----------WAEAEKGNVLEVKEL 370
            .|||..|..:       .::..|| .|.:.|    |.||:          |         ::.|
  Rat   471 TEHSWADAPIIGHLWEFVLATDTF-HLGYTETGHCVGEPNTKLPPPQRMQW---------DIPE- 524

  Fly   371 HFQLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHK 435
              |....::|.. :|.|.:.|   ||.:....|..:||..:|..|..||:|||:.:|.|:::...
  Rat   525 --QCQTAIENSY-QVAKALAD---DVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKG 583

  Fly   436 EIAPTYETALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEAR 500
            :...|||.::.|.:..|||||:|||||....|:||..........|...||:|.::|::....|.
  Rat   584 KFCLTYEASMTRMFREGRTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAM 648

  Fly   501 KGHGIDRHLFGLWCAAYE------------------SKMDIPAF----YDDPMYTKS-GGGGNFV 542
            .|.|||||||.|:..:..                  |...||.|    :|...|... |.||.|
  Rat   649 TGAGIDRHLFCLYIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGF- 712

  Fly   543 LSSSTLGFTANVGFVAPMVFDGYGVFYSITSE-AVFINTTAYRDSLKT---SARKFN-------- 595
                           .|:...||||.|.|..| .:|.:.::...|.:|   :|.:|.
  Rat   713 ---------------GPVADHGYGVSYMIAGENTMFFHVSSKLSSSETFPQNALRFGNHIRQALL 762

  Fly   596 ---DIFKDS 601
               |:||.|
  Rat   763 DIADLFKIS 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CROT	NP_733230.1	Carn_acyltransf	26..594	CDD:459926	167/630 (27%)
Cpt1b	XP_006242242.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	176..759	CDD:459926	168/636 (26%)